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Patient P-01727

Synthetic patientNBL-101 · Day 107 · 25–34 · F · baseline S03Steering view · 3DOpen companion preview
Therapy response
Stable
Tolerance
Favorable
GI state
Improving
Inflammatory state
Favorable
Nutritional resilience
Favorable
Discontinuation risk
6%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 NBL-101 started — Baseline state S03
  2. Day 12 Trajectory diverged from prediction — Observed response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 12.

Primary contributors, last 14 days
  • GI instability-6
  • Inflammatory activity-4
  • Nutritional resilience-4

What helped?

No interventions yet.

    LIFE OS recommendation
    No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

    Daily trackers

    Molecule settings

    The trackers this program marks as important, last 14 days vs the 14 before.

    GI burden
    Companion
    8.2/100
    worsening · +10.8 vs previous 14 d
    Toxicity
    Blood
    14.8/100
    worsening · +6.4 vs previous 14 d
    Sleep quality
    Wearable
    65.8/100
    worsening · -3.3 vs previous 14 d
    Energy level
    Daily log
    6.9/10
    worsening · -0.7 vs previous 14 d
    Stress level
    Daily log
    4.5/10
    worsening · +0.7 vs previous 14 d
    Steps
    Wearable
    8,147
    worsening · -921 vs previous 14 d
    Adherence
    Companion
    92.9 %
    improving · +6.8 vs previous 14 d
    This trajectory is doing well — what to keep, what to watch
    Steering view →

    Heading towards restoration · 82 from the failing basin, 27 from restoration.

    Good elements to keep
    • Daily walks resumed
      perturbation · steering +3.3
    Main detractors to watch
    • Low butyrate capacity
      hidden · steering -17.5
    • Dietary fat load
      perturbation · steering -11.2
    • Alcohol
      perturbation · steering -8.3
    • Poor-sleep week
      perturbation · steering -3
    • Dietary fat load
      detractor · GI +6.7 next day
    • Alcohol
      detractor · GI +5.7 next day
    State influencers · digestive

    Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

    • Dietary fat load
      +6.7detractor · 95%
    • Alcohol
      +5.7detractor · 95%
    • Simple carbohydrates
      +1.5no signal · 27%
    • Spicy / capsaicin
      +0.9no signal · 15%
    • Insoluble fibre
      +0.5no signal · 15%
    • Histamine load
      +0.1no signal · 15%

    Biological layers

    Which pathways look influenced, and by which layer of this person's biology.

    Pathways under pressure
    • Butyrate / short-chain fatty acid production ↓60
      • MicrobiomeButyrate capacity 32/100
      • MicrobiomeF. prausnitzii depleted
    • Drug metabolism and exposure ↑35
      • DNADPYD *2A → slower clearance
    • Mucosal barrier integrity ↓30
      • MicrobiomeAkkermansia low → thinner mucus layer
    • Inflammatory signalling ↓15
      • WearableHRV 38 ms, trending down
    DNA
    Fictional pharmacogenomic panel
    • DPYD *2A heterozygous
      Slower drug clearance
    • CYP2D6 Normal metabolizer
      Expected exposure
    Microbiome
    Shannon diversity 3 · butyrate capacity 32/100
    • Akkermansia muciniphilaLow
    • Faecalibacterium prausnitziiLow
    • Bacteroides fragilisNormal
    • Bifidobacterium longumLow
    • EnterobacteriaceaeNormal
    Wearable, last 14 days
    daily evolution fed into the runtime
    HRV
    37 ms
    Sleep
    7.2 h
    Steps
    7,694
    Resting HR
    57 bpm
    Daily log: GI score 8, nutritional resilience 71, adherence 93.

    What this patient sees in NostraAI

    The content that steers the trajectory: what to eat, what to do, what to take.

    Open companion preview
    What to eat
    • Keep meals regular; three to four moderate portions spaced through the day
    • Include a cooked vegetable portion with each main meal
    • Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
    • Avoid known triggers for now: fried or oily food, dairy, alcohol
    What to do
    • Log the daily check-in; one line is enough
    • Keep the current walking rhythm
    • Keep the sleep window steady
    • Keep hydration steady: small amounts through the day rather than large volumes at once
    What to take
    • Take the scheduled dose as agreed with your care team
    • No additional supplements this week
    • Fictional demo item: continue vitamin D as before

    284 biologically similar trajectories

    Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

    Sort by similaritySort by interventionSort by outcomeSort by stateSort by response
    PatientSimilarityBaselineInterventionOutcomeResponse today
    P-0154135%S09AD-05no change43
    P-0167935%S12AD-05no change39
    P-0137733%S11AD-05no change42
    P-0148333%S14AD-05no change35
    P-0180433%S19AD-05improved61
    P-0177330%S05AD-05improved27
    P-0184828%S05AD-05no change23
    P-0135034%S19BR-03no change34
    P-0131333%S01BR-03improved32
    P-0146832%S06BR-03no change41
    P-0145031%S09BR-03no change36
    P-0168930%S13BR-03no change50