Patient P-01732
Synthetic patientNBL-101 · Day 104 · 65–74 · M · baseline S14Steering view · 3DOpen companion preview
Therapy response
Stable
Tolerance
Deteriorating
GI state
Unstable
Inflammatory state
Unstable
Nutritional resilience
Unstable
Discontinuation risk
94%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S14
- Day 45 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 57 ME-01 recommended — Monitoring Escalation ME-01
- Day 58 Patient accepted — Started ME-01 in the companion
- Day 61 Deterioration detected before clinical escalation — Monitoring Escalation ME-01
What changed?
Trajectory began diverging from predicted response on Day 45.
Primary contributors, last 14 days
- Toxicity+11
- GI instability-5
- Inflammatory activity+4
What helped?
- Monitoring Escalation ME-01Day 57Result: deterioration detected before clinical escalation
LIFE OS recommendation
GI Support Protocol GI-04
90%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 83% showed improvement
- median effect visible after 8 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
GI burden
Companion59.4/100
worsening · +4.6 vs previous 14 d
Toxicity
Blood56/100
worsening · +4.8 vs previous 14 d
Sleep quality
Wearable21.7/100
worsening · -1.7 vs previous 14 d
Energy level
Daily log2.7/10
worsening · -0.6 vs previous 14 d
Stress level
Daily log6.8/10
stable · +0.2 vs previous 14 d
Steps
Wearable6,921
worsening · -527 vs previous 14 d
Adherence
Companion44.6 %
improving · +7.9 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards restoration · 23 from the failing basin, 67 from restoration.
Would help
Would not help
- Keep fat lowGI +5.4 next day on high-intake days · n 23
- Keep simple carbs lowGI +5.4 next day on high-intake days · n 14
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Dietary fat load+5.4detractor · 95%
- Simple carbohydrates+5.4detractor · 95%
- Insoluble fibre+2.2no signal · 49%
- Alcohol-0.6no signal · 15%
- Histamine load-0.3no signal · 15%
- Spicy / capsaicin0no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Butyrate / short-chain fatty acid production ↓80
- MicrobiomeButyrate capacity 39/100
- MicrobiomeF. prausnitzii depleted
- Daily logFibre intake low in recent food logs
- Mucosal barrier integrity ↓60
- MicrobiomeAkkermansia low → thinner mucus layer
- Daily logGI symptom score 59 and rising
- WearableSleep 6.1 h, below personal baseline
- Inflammatory signalling ↑45
- MicrobiomeBacteroides fragilis expansion
- BloodInflammatory load index 63
- Autonomic recovery ↓45
- WearableResting HR 81 bpm
- WearableShort sleep window
- Drug metabolism and exposure ↑20
- BloodToxicity index 56
DNA
Fictional pharmacogenomic panel
- CYP2D6 Rapid metabolizerExpected exposure
Microbiome
Shannon diversity 2.6 · butyrate capacity 39/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisHigh
- Bifidobacterium longumNormal
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 38 ms
- Sleep
- 5.8 h
- Steps
- 6,672
- Resting HR
- 80 bpm
Daily log: GI score 59, nutritional resilience 40, adherence 45.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- Keep the current walking rhythm
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-01804 | 19% | S19 | AD-05 | improved | 61 |
| P-01689 | 19% | S13 | BR-03 | no change | 50 |
| P-01708 | 30% | S07 | CR-01 | improved | 59 |
| P-01371 | 26% | S06 | CR-01 | improved | 63 |
| P-01696 | 26% | S20 | CR-01 | improved | 59 |
| P-01835 | 26% | S17 | CR-01 | improved | 56 |
| P-01388 | 25% | S17 | CR-01 | improved | 59 |
| P-01442 | 24% | S13 | CR-01 | improved | 61 |
| P-01877 | 24% | S01 | CR-01 | improved | 67 |
| P-01430 | 19% | S05 | CR-01 | improved | 54 |
| P-01767 | 19% | S14 | DT-01 | no change | 63 |
| P-01646 | 59% | S14 | GI-04 | no change | 42 |