Patient P-01743
Synthetic patientNBL-101 · Day 119 · 25–34 · F · baseline S14Steering view · 3DOpen companion preview
Therapy response
Improving
Tolerance
Unstable
GI state
Unstable
Inflammatory state
Unstable
Nutritional resilience
Unstable
Discontinuation risk
96%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S14
- Day 50 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 50 SC-12 recommended — Supportive Compound SC-12
- Day 51 Patient accepted — Started SC-12 in the companion
- Day 57 No meaningful change — Supportive Compound SC-12
What changed?
Trajectory began diverging from predicted response on Day 50.
Primary contributors, last 14 days
- Toxicity+18
- GI instability-12
- Nutritional resilience+6
- Inflammatory activity+4
- Treatment adherence-3
What helped?
- Supportive Compound SC-12Day 50Result: no meaningful change
LIFE OS recommendation
GI Support Protocol GI-04
92%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 84% showed improvement
- median effect visible after 8 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
GI burden
Companion67.3/100
stable · -2.8 vs previous 14 d
Toxicity
Blood63.1/100
worsening · +7.5 vs previous 14 d
Sleep quality
Wearable28.4/100
worsening · -1.9 vs previous 14 d
Energy level
Daily log1.6/10
worsening · -0.2 vs previous 14 d
Stress level
Daily log7/10
stable · +0.2 vs previous 14 d
Steps
Wearable5,509
worsening · -304 vs previous 14 d
Adherence
Companion41.7 %
stable · +0.6 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards restoration · 28 from the failing basin, 74 from restoration.
Would help
Would not help
- SC-12 Supportive Compoundalready tried, no meaningful change
- Keep fat lowGI +5.5 next day on high-intake days · n 23
- Keep histamine lowGI +5.1 next day on high-intake days · n 18
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Dietary fat load+5.5detractor · 95%
- Histamine load+5.1detractor · 95%
- Simple carbohydrates+2.5no signal · 45%
- Alcohol+1.9no signal · 40%
- Insoluble fibre-0.3no signal · 15%
- Spicy / capsaicin+0.3no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Inflammatory signalling ↑70
- DNAIL6 -174 variant raises baseline inflammatory tone
- MicrobiomeBacteroides fragilis expansion
- BloodInflammatory load index 70
- Mucosal barrier integrity ↓60
- DNAFUT2 non-secretor lowers mucosal fucosylation
- Daily logGI symptom score 67 and rising
- WearableSleep 5.6 h, below personal baseline
- Drug metabolism and exposure ↑60
- DNACYP2D6 poor metabolizer → higher exposure
- BloodToxicity index 63
- Butyrate / short-chain fatty acid production ↓55
- MicrobiomeButyrate capacity 37/100
- Daily logFibre intake low in recent food logs
- Autonomic recovery ↑45
- WearableResting HR 74 bpm
- WearableShort sleep window
DNA
Fictional pharmacogenomic panel
- FUT2 rs601338 AA (non-secretor)Reduced mucosal fucosylation
- IL6 -174 G/CHigher inflammatory tone
- CYP2D6 Poor metabolizerHigher exposure at standard dose
Microbiome
Shannon diversity 2.5 · butyrate capacity 37/100
- Akkermansia muciniphilaNormal
- Faecalibacterium prausnitziiNormal
- Bacteroides fragilisHigh
- Bifidobacterium longumLow
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 40 ms
- Sleep
- 5.2 h
- Steps
- 5,962
- Resting HR
- 74 bpm
Daily log: GI score 67, nutritional resilience 36, adherence 42.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- Keep the current walking rhythm
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-01612 | 53% | S14 | ME-01 | improved | 51 |
| P-01615 | 49% | S14 | ME-01 | improved | 48 |
| P-01728 | 49% | S14 | SC-12 | improved | 41 |
| P-01531 | 48% | S14 | ME-01 | improved | 51 |
| P-01720 | 47% | S14 | NP-02 | improved | 47 |
| P-01897 | 44% | S14 | ME-01 | improved | 43 |
| P-01605 | 43% | S14 | ME-01 | improved | 41 |
| P-01736 | 42% | S03 | ME-01 | improved | 46 |
| P-01751 | 42% | S14 | ME-01 | improved | 48 |
| P-01412 | 41% | S14 | NP-02 | improved | 49 |
| P-01564 | 41% | S14 | ME-01 | improved | 39 |
| P-01845 | 41% | S14 | NP-02 | improved | 47 |