Patient P-01752
Synthetic patientNBL-101 · Day 97 · 55–64 · F · baseline S20Steering view · 3DOpen companion preview
Therapy response
Declining
Tolerance
Deteriorating
GI state
Deteriorating
Inflammatory state
Deteriorating
Nutritional resilience
Declining
Discontinuation risk
28%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S20
- Day 10 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 14 DT-01 recommended — Dosing / Timing Recommendation DT-01
- Day 15 Patient accepted — Started DT-01 in the companion
- Day 20 GI symptom burden −23% vs expected — Dosing / Timing Recommendation DT-01
- Day 26 Tolerance state changed — Unstable → Improving
What changed?
Trajectory began diverging from predicted response on Day 10.
Primary contributors, last 14 days
- GI instability+11
- Inflammatory activity+11
- Nutritional resilience-8
- Toxicity+7
- Treatment adherence+3
What helped?
- Dosing / Timing Recommendation DT-01Day 14Result: symptom burden −23%
LIFE OS recommendation
No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
GI burden
Companion26.5/100
worsening · +7.0 vs previous 14 d
Toxicity
Blood18.2/100
worsening · +1.9 vs previous 14 d
Sleep quality
Wearable23.8/100
worsening · -3.4 vs previous 14 d
Energy level
Daily log4.7/10
worsening · -0.5 vs previous 14 d
Stress level
Daily log4.5/10
worsening · +0.2 vs previous 14 d
Steps
Wearable5,971
stable · -134 vs previous 14 d
Adherence
Companion100 %
stable · +0.4 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards failing · 62 from the failing basin, 30 from restoration.
Would help
- No untried action with strong evidence. Compose one from primitives.
Would not help
- Keep fat lowGI +4.8 next day on high-intake days · n 17
- Keep simple carbs lowGI +3.4 next day on high-intake days · n 20
- Keep spicy lowGI +3 next day on high-intake days · n 25
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Dietary fat load+4.8detractor · 95%
- Simple carbohydrates+3.4detractor · 94%
- Spicy / capsaicin+3detractor · 79%
- Histamine load+0.7no signal · 18%
- Alcohol+0.6no signal · 15%
- Insoluble fibre-0.4no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Butyrate / short-chain fatty acid production ↓60
- MicrobiomeButyrate capacity 44/100
- MicrobiomeF. prausnitzii depleted
- Inflammatory signalling ↑45
- DNAIL6 -174 variant raises baseline inflammatory tone
- MicrobiomeBacteroides fragilis expansion
- Autonomic recovery ↑45
- WearableResting HR 74 bpm
- WearableShort sleep window
- Mucosal barrier integrity ↓40
- MicrobiomeAkkermansia low → thinner mucus layer
- WearableSleep 5.3 h, below personal baseline
- Drug metabolism and exposure ↑35
- DNADPYD *2A → slower clearance
DNA
Fictional pharmacogenomic panel
- IL6 -174 G/CHigher inflammatory tone
- DPYD *2A heterozygousSlower drug clearance
- CYP2D6 Normal metabolizerExpected exposure
Microbiome
Shannon diversity 2.5 · butyrate capacity 44/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisHigh
- Bifidobacterium longumLow
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 49 ms
- Sleep
- 5.9 h
- Steps
- 5,673
- Resting HR
- 71 bpm
Daily log: GI score 27, nutritional resilience 61, adherence 100.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Keep meals regular; three to four moderate portions spaced through the day
- Include a cooked vegetable portion with each main meal
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Log the daily check-in; one line is enough
- Keep the current walking rhythm
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- No additional supplements this week
- Fictional demo item: continue vitamin D as before
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-01861 | 53% | S12 | HY-01 | improved | 47 |
| P-01342 | 49% | S11 | DT-01 | improved | 48 |
| P-01374 | 46% | S08 | HY-01 | improved | 49 |
| P-01555 | 46% | S06 | GI-04 | improved | 56 |
| P-01346 | 45% | S12 | DT-01 | improved | 52 |
| P-01593 | 44% | S10 | HY-01 | improved | 56 |
| P-01385 | 41% | S06 | HY-01 | improved | 50 |
| P-01618 | 41% | S10 | GI-04 | improved | 39 |
| P-01455 | 40% | S01 | GI-04 | improved | 61 |
| P-01724 | 39% | S10 | DT-01 | improved | 63 |
| P-01430 | 38% | S05 | CR-01 | improved | 54 |
| P-01571 | 38% | S13 | SC-12 | improved | 57 |