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Patient P-01754

Synthetic patientNBL-101 · Day 116 · 45–54 · M · baseline S14Steering view · 3DOpen companion preview
Therapy response
Improving
Tolerance
Favorable
GI state
Deteriorating
Inflammatory state
Deteriorating
Nutritional resilience
Declining
Discontinuation risk
45%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 NBL-101 started — Baseline state S14
  2. Day 56 Trajectory diverged from prediction — Observed response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 56.

Primary contributors, last 14 days
  • Nutritional resilience-13
  • GI instability+12
  • Inflammatory activity+9
  • Treatment adherence+4
  • Toxicity-3

What helped?

No interventions yet.

    LIFE OS recommendation
    No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

    Daily trackers

    Molecule settings

    The trackers this program marks as important, last 14 days vs the 14 before.

    GI burden
    Companion
    30.9/100
    improving · -6.3 vs previous 14 d
    Toxicity
    Blood
    18.3/100
    improving · -6.8 vs previous 14 d
    Sleep quality
    Wearable
    37.5/100
    stable · +1.4 vs previous 14 d
    Energy level
    Daily log
    5.3/10
    improving · +0.9 vs previous 14 d
    Stress level
    Daily log
    3.5/10
    improving · -0.5 vs previous 14 d
    Steps
    Wearable
    3,375
    improving · +576 vs previous 14 d
    Adherence
    Companion
    91.9 %
    stable · +2.9 vs previous 14 d
    This trajectory is decaying — what would help, what would not
    Steering view →

    Heading towards failing · 68 from the failing basin, 19 from restoration.

    Would help
    • No untried action with strong evidence. Compose one from primitives.
    Would not help
    • Keep histamine low
      GI +6.7 next day on high-intake days · n 18
    • Keep alcohol low
      GI +4 next day on high-intake days · n 17
    • Keep fibre low
      GI +2.9 next day on high-intake days · n 18
    State influencers · digestive

    Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

    • Histamine load
      +6.7detractor · 95%
    • Alcohol
      +4detractor · 93%
    • Insoluble fibre
      +2.9detractor · 59%
    • Spicy / capsaicin
      +0.3no signal · 15%
    • Dietary fat load
      +0.1no signal · 15%
    • Simple carbohydrates
      -0.1no signal · 15%

    Biological layers

    Which pathways look influenced, and by which layer of this person's biology.

    Pathways under pressure
    • Mucosal barrier integrity ↓40
      • DNAFUT2 non-secretor lowers mucosal fucosylation
      • WearableSleep 5.6 h, below personal baseline
    • Autonomic recovery ↓40
      • Wearable3,375 steps/day
      • WearableShort sleep window
    • Inflammatory signalling ↑20
      • MicrobiomeBacteroides fragilis expansion
    DNA
    Fictional pharmacogenomic panel
    • FUT2 rs601338 AA (non-secretor)
      Reduced mucosal fucosylation
    • CYP2D6 Rapid metabolizer
      Expected exposure
    Microbiome
    Shannon diversity 3.2 · butyrate capacity 48/100
    • Akkermansia muciniphilaNormal
    • Faecalibacterium prausnitziiNormal
    • Bacteroides fragilisHigh
    • Bifidobacterium longumNormal
    • EnterobacteriaceaeHigh
    Wearable, last 14 days
    daily evolution fed into the runtime
    HRV
    63 ms
    Sleep
    6.6 h
    Steps
    3,778
    Resting HR
    67 bpm
    Daily log: GI score 31, nutritional resilience 54, adherence 92.

    What this patient sees in NostraAI

    The content that steers the trajectory: what to eat, what to do, what to take.

    Open companion preview
    What to eat
    • Keep meals regular; three to four moderate portions spaced through the day
    • Include a cooked vegetable portion with each main meal
    • Keep fibre steady; no new sources this week
    • Avoid known triggers for now: fried or oily food, dairy, alcohol
    What to do
    • Log the daily check-in; one line is enough
    • A 15-minute walk after lunch
    • Protect a 7.5-hour sleep window; screens off 30 minutes before
    • Keep hydration steady: small amounts through the day rather than large volumes at once
    What to take
    • Take the scheduled dose as agreed with your care team
    • No additional supplements this week
    • Fictional demo item: continue vitamin D as before

    284 biologically similar trajectories

    Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

    Sort by similaritySort by interventionSort by outcomeSort by stateSort by response
    PatientSimilarityBaselineInterventionOutcomeResponse today
    P-0157143%S13SC-12improved57
    P-0172442%S10DT-01improved63
    P-0145539%S01GI-04improved61
    P-0143036%S05CR-01improved54
    P-0155536%S06GI-04improved56
    P-0159336%S10HY-01improved56
    P-0175236%S20DT-01improved50
    P-0180436%S19AD-05improved61
    P-0134234%S11DT-01improved48
    P-0186134%S12HY-01improved47
    P-0132133%S12GI-04improved53
    P-0134633%S12DT-01improved52