Patient P-01761

Synthetic patientNBL-101 · Day 113 · 45–54 · M · baseline S10Steering view · 3D Open companion preview

Therapy response

Unstable

Tolerance

Improving

GI state

Favorable

Inflammatory state

Favorable

Nutritional resilience

Improving

Discontinuation risk

22%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 NBL-101 started — Baseline state S10
Day 26 Trajectory diverged from prediction — Observed response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 26.

Primary contributors, last 14 days

Treatment adherence+11
Toxicity-8
Nutritional resilience+4
Inflammatory activity-2

What helped?

No interventions yet.

LIFE OS recommendation

No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

GI burden

Companion

31.1/100

worsening · +8.7 vs previous 14 d

Toxicity

Blood

15.5/100

worsening · +3.5 vs previous 14 d

Sleep quality

Wearable

28.7/100

worsening · -4.4 vs previous 14 d

Energy level

Daily log

4.9/10

worsening · -0.3 vs previous 14 d

Stress level

Daily log

4.7/10

worsening · +0.5 vs previous 14 d

Steps

Wearable

4,432

worsening · -563 vs previous 14 d

Adherence

Companion

89 %

stable · -1.2 vs previous 14 d

This trajectory is decaying — what would help, what would not

Steering view →

Heading towards failing · 54 from the failing basin, 49 from restoration.

Would help

No untried action with strong evidence. Compose one from primitives.

Would not help

Keep simple carbs low
GI +2.5 next day on high-intake days · n 19
Keep fibre low
GI +1.8 next day on high-intake days · n 17

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Simple carbohydrates
+2.5detractor · 90%
Insoluble fibre
+1.8detractor · 56%
Dietary fat load
-1.6no signal · 44%
Alcohol
+0.7no signal · 18%
Histamine load
+0.1no signal · 15%
Spicy / capsaicin
0no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Drug metabolism and exposure ↑35
- DNADPYD *2A → slower clearance
Butyrate / short-chain fatty acid production ↓25
- MicrobiomeF. prausnitzii depleted
Autonomic recovery ↑20
- WearableShort sleep window
Inflammatory signalling ↓15
- WearableHRV 30 ms, trending down

DNA

Fictional pharmacogenomic panel

DPYD *2A heterozygous
Slower drug clearance
CYP2D6 Normal metabolizer
Expected exposure

Microbiome

Shannon diversity 2.9 · butyrate capacity 81/100

Akkermansia muciniphilaNormal
Faecalibacterium prausnitziiLow
Bacteroides fragilisNormal
Bifidobacterium longumNormal
EnterobacteriaceaeNormal

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 29 ms
Sleep: 6.1 h
Steps: 4,056
Resting HR: 62 bpm

Daily log: GI score 31, nutritional resilience 62, adherence 89.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
Avoid known triggers for now: fried or oily food, dairy, alcohol

What to do

Log the daily check-in; one line is enough
A 15-minute walk after lunch
Protect a 7.5-hour sleep window; screens off 30 minutes before
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the scheduled dose as agreed with your care team
No additional supplements this week
Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-01773	42%	S05	AD-05	improved	27
P-01483	31%	S14	AD-05	no change	35
P-01679	31%	S12	AD-05	no change	39
P-01377	30%	S11	AD-05	no change	42
P-01541	29%	S09	AD-05	no change	43
P-01848	28%	S05	AD-05	no change	23
P-01804	27%	S19	AD-05	improved	61
P-01313	33%	S01	BR-03	improved	32
P-01350	31%	S19	BR-03	no change	34
P-01450	29%	S09	BR-03	no change	36
P-01468	26%	S06	BR-03	no change	41
P-01689	26%	S13	BR-03	no change	50