Patient P-01772
Synthetic patientNBL-101 · Day 115 · 55–64 · M · baseline S20Steering view · 3DOpen companion preview
Therapy response
Improving
Tolerance
Deteriorating
GI state
Unstable
Inflammatory state
Unstable
Nutritional resilience
Unstable
Discontinuation risk
96%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S20
- Day 31 NP-02 recommended — Dietary Support Protocol NP-02
- Day 32 Patient accepted — Started NP-02 in the companion
- Day 42 No meaningful change — Dietary Support Protocol NP-02
- Day 49 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 49 SC-12 recommended — Supportive Compound SC-12
- Day 50 Patient declined — Not now
What changed?
Trajectory began diverging from predicted response on Day 49.
Primary contributors, last 14 days
- Inflammatory activity+11
- Toxicity+10
- GI instability+7
- Treatment adherence+2
What helped?
- Dietary Support Protocol NP-02Day 31Result: no meaningful change
- Supportive Compound SC-12Day 49Declined by patient
LIFE OS recommendation
GI Support Protocol GI-04
92%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 83% showed improvement
- median effect visible after 8 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
GI burden
Companion72.4/100
worsening · +7.8 vs previous 14 d
Toxicity
Blood54.3/100
improving · -8.4 vs previous 14 d
Sleep quality
Wearable14.6/100
worsening · -2.1 vs previous 14 d
Energy level
Daily log1.4/10
improving · +0.1 vs previous 14 d
Stress level
Daily log6.9/10
stable · +0.1 vs previous 14 d
Steps
Wearable500
worsening · -128 vs previous 14 d
Adherence
Companion42.7 %
improving · +2.3 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards failing · 27 from the failing basin, 76 from restoration.
Would help
Would not help
- NP-02 Dietary Support Protocolalready tried, no meaningful change
- Keep fat lowGI +3.8 next day on high-intake days · n 23
- Keep histamine lowGI +3.8 next day on high-intake days · n 25
- Keep spicy lowGI +2.7 next day on high-intake days · n 29
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Dietary fat load+3.8detractor · 95%
- Histamine load+3.8detractor · 95%
- Spicy / capsaicin+2.7detractor · 95%
- Simple carbohydrates+2.1detractor · 70%
- Alcohol+1.7no signal · 53%
- Insoluble fibre-0.6no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Mucosal barrier integrity ↓90
- DNAFUT2 non-secretor lowers mucosal fucosylation
- MicrobiomeAkkermansia low → thinner mucus layer
- Daily logGI symptom score 72 and rising
- WearableSleep 5.1 h, below personal baseline
- Inflammatory signalling ↑85
- DNAIL6 -174 variant raises baseline inflammatory tone
- MicrobiomeBacteroides fragilis expansion
- BloodInflammatory load index 68
- WearableHRV 38 ms, trending down
- Butyrate / short-chain fatty acid production ↓80
- MicrobiomeButyrate capacity 29/100
- MicrobiomeF. prausnitzii depleted
- Daily logFibre intake low in recent food logs
- Autonomic recovery ↓65
- WearableResting HR 73 bpm
- Wearable500 steps/day
- WearableShort sleep window
- Drug metabolism and exposure ↑55
- DNADPYD *2A → slower clearance
- BloodToxicity index 54
DNA
Fictional pharmacogenomic panel
- FUT2 rs601338 AA (non-secretor)Reduced mucosal fucosylation
- IL6 -174 G/CHigher inflammatory tone
- DPYD *2A heterozygousSlower drug clearance
- CYP2D6 Rapid metabolizerExpected exposure
Microbiome
Shannon diversity 2.1 · butyrate capacity 29/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisHigh
- Bifidobacterium longumNormal
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 42 ms
- Sleep
- 4.9 h
- Steps
- 608
- Resting HR
- 70 bpm
Daily log: GI score 72, nutritional resilience 32, adherence 43.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- A 15-minute walk after lunch
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-01813 | 45% | S01 | NP-02 | no change | 40 |
| P-01327 | 35% | S01 | GI-04 | improved | 56 |
| P-01310 | 30% | S01 | — | — | 57 |
| P-01688 | 28% | S01 | GI-04 | improved | 40 |
| P-01877 | 26% | S01 | CR-01 | improved | 67 |
| P-01604 | 18% | S01 | — | — | 71 |
| P-01821 | 18% | S01 | — | — | 58 |
| P-01823 | 18% | S01 | — | — | 57 |
| P-01452 | 32% | S02 | GI-04 | improved | 46 |
| P-01635 | 31% | S02 | GI-04 | improved | 49 |
| P-01459 | 26% | S02 | — | — | 51 |
| P-01498 | 18% | S02 | — | — | 56 |