Patient P-01775
Synthetic patientNBL-101 · Day 112 · 45–54 · M · baseline S14Steering view · 3DOpen companion preview
Therapy response
Improving
Tolerance
Favorable
GI state
Unstable
Inflammatory state
Improving
Nutritional resilience
Unstable
Discontinuation risk
84%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S14
- Day 31 NP-02 recommended — Dietary Support Protocol NP-02
- Day 32 Patient accepted — Started NP-02 in the companion
- Day 42 No meaningful change — Dietary Support Protocol NP-02
- Day 44 SC-12 recommended — Supportive Compound SC-12
- Day 45 Patient accepted — Started SC-12 in the companion
- Day 47 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 51 GI symptom burden −24% vs expected — Supportive Compound SC-12
- Day 57 Tolerance state changed — Unstable → Improving
What changed?
Trajectory began diverging from predicted response on Day 47.
Primary contributors, last 14 days
- Inflammatory activity-8
- Treatment adherence-6
- Nutritional resilience+5
- GI instability-4
- Toxicity-4
What helped?
- Dietary Support Protocol NP-02Day 31Result: no meaningful change
- Supportive Compound SC-12Day 44Result: symptom burden −24%
LIFE OS recommendation
GI Support Protocol GI-04
88%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 83% showed improvement
- median effect visible after 8 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
GI burden
Companion60.6/100
worsening · +3.8 vs previous 14 d
Toxicity
Blood29.4/100
improving · -3.0 vs previous 14 d
Sleep quality
Wearable16.9/100
stable · -0.4 vs previous 14 d
Energy level
Daily log2.9/10
stable · +0.1 vs previous 14 d
Stress level
Daily log7.3/10
stable · -0.1 vs previous 14 d
Steps
Wearable6,498
stable · +152 vs previous 14 d
Adherence
Companion46.3 %
stable · -1.8 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards restoration · 32 from the failing basin, 59 from restoration.
Would help
Would not help
- NP-02 Dietary Support Protocolalready tried, no meaningful change
- Keep fat lowGI +6.6 next day on high-intake days · n 23
- Keep histamine lowGI +5.8 next day on high-intake days · n 23
- Keep alcohol lowGI +5.8 next day on high-intake days · n 22
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Dietary fat load+6.6detractor · 95%
- Histamine load+5.8detractor · 95%
- Alcohol+5.8detractor · 95%
- Spicy / capsaicin+5detractor · 95%
- Insoluble fibre+4.4detractor · 87%
- Simple carbohydrates-2.6no signal · 47%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Mucosal barrier integrity ↓90
- DNAFUT2 non-secretor lowers mucosal fucosylation
- MicrobiomeAkkermansia low → thinner mucus layer
- Daily logGI symptom score 61 and rising
- WearableSleep 5.6 h, below personal baseline
- Inflammatory signalling ↓85
- DNAIL6 -174 variant raises baseline inflammatory tone
- MicrobiomeBacteroides fragilis expansion
- BloodInflammatory load index 50
- WearableHRV 21 ms, trending down
- Butyrate / short-chain fatty acid production ↓55
- MicrobiomeButyrate capacity 24/100
- Daily logFibre intake low in recent food logs
- Autonomic recovery ↑45
- WearableResting HR 74 bpm
- WearableShort sleep window
DNA
Fictional pharmacogenomic panel
- FUT2 rs601338 AA (non-secretor)Reduced mucosal fucosylation
- IL6 -174 G/CHigher inflammatory tone
- CYP2D6 Rapid metabolizerExpected exposure
- MTHFR C677TReduced folate turnover
Microbiome
Shannon diversity 3 · butyrate capacity 24/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiNormal
- Bacteroides fragilisHigh
- Bifidobacterium longumNormal
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 19 ms
- Sleep
- 5.6 h
- Steps
- 5,586
- Resting HR
- 74 bpm
Daily log: GI score 61, nutritional resilience 40, adherence 46.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- Keep the current walking rhythm
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-01327 | 49% | S01 | GI-04 | improved | 56 |
| P-01813 | 41% | S01 | NP-02 | no change | 40 |
| P-01688 | 38% | S01 | GI-04 | improved | 40 |
| P-01310 | 29% | S01 | — | — | 57 |
| P-01877 | 26% | S01 | CR-01 | improved | 67 |
| P-01821 | 22% | S01 | — | — | 58 |
| P-01823 | 22% | S01 | — | — | 57 |
| P-01604 | 21% | S01 | — | — | 71 |
| P-01846 | 21% | S01 | — | — | 37 |
| P-01635 | 36% | S02 | GI-04 | improved | 49 |
| P-01452 | 33% | S02 | GI-04 | improved | 46 |
| P-01459 | 28% | S02 | — | — | 51 |