Patient P-01776
Therapy response
Declining
Tolerance
Improving
GI state
Unstable
Inflammatory state
Unstable
Nutritional resilience
Unstable
Discontinuation risk
93%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S16
- Day 31 NP-02 recommended — Dietary Support Protocol NP-02
- Day 32 Patient accepted — Started NP-02 in the companion
- Day 42 No meaningful change — Dietary Support Protocol NP-02
- Day 47 Trajectory diverged from prediction — Observed response fell below the model's expected path.
What changed?
Trajectory began diverging from predicted response on Day 47.
Primary contributors, last 14 days
- Nutritional resilience-6
- Toxicity-5
- GI instability+3
- Inflammatory activity-3
What helped?
- Dietary Support Protocol NP-02Day 31Result: no meaningful change
LIFE OS recommendation
GI Support Protocol GI-04
87%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 83% showed improvement
- median effect visible after 8 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
GI burden
Companion67.3/100
worsening · +3.6 vs previous 14 d
Toxicity
Blood57.4/100
improving · -7.1 vs previous 14 d
Sleep quality
Wearable12.6/100
improving · +1.7 vs previous 14 d
Energy level
Daily log1.8/10
improving · +0.1 vs previous 14 d
Stress level
Daily log8/10
stable · -0.0 vs previous 14 d
Steps
Wearable5,950
stable · -59 vs previous 14 d
Adherence
Companion40.5 %
worsening · -1.9 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards failing · 24 from the failing basin, 71 from restoration.
Would help
Would not help
- NP-02 Dietary Support Protocolalready tried, no meaningful change
- Keep fat lowGI +7.4 next day on high-intake days · n 28
- Keep simple carbs lowGI +4.7 next day on high-intake days · n 22
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Dietary fat load+7.4detractor · 95%
- Simple carbohydrates+4.7detractor · 95%
- Histamine load-0.3no signal · 15%
- Alcohol-0.3no signal · 15%
- Insoluble fibre-0.2no signal · 15%
- Spicy / capsaicin+0.2no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Inflammatory signalling ↓60
- MicrobiomeBacteroides fragilis expansion
- BloodInflammatory load index 63
- WearableHRV 15 ms, trending down
- Butyrate / short-chain fatty acid production ↓55
- MicrobiomeButyrate capacity 27/100
- Daily logFibre intake low in recent food logs
- Mucosal barrier integrity ↓30
- Daily logGI symptom score 67 and rising
- WearableSleep 5.4 h, below personal baseline
- Drug metabolism and exposure ↑20
- BloodToxicity index 57
- Autonomic recovery ↑20
- WearableShort sleep window
DNA
Fictional pharmacogenomic panel
- CYP2D6 Normal metabolizerExpected exposure
- MTHFR C677TReduced folate turnover
Microbiome
Shannon diversity 2.9 · butyrate capacity 27/100
- Akkermansia muciniphilaNormal
- Faecalibacterium prausnitziiNormal
- Bacteroides fragilisHigh
- Bifidobacterium longumLow
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 16 ms
- Sleep
- 5.2 h
- Steps
- 5,940
- Resting HR
- 70 bpm
Daily log: GI score 67, nutritional resilience 31, adherence 41.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- Keep the current walking rhythm
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-01804 | 17% | S19 | AD-05 | improved | 61 |
| P-01377 | 16% | S11 | AD-05 | no change | 42 |
| P-01350 | 16% | S19 | BR-03 | no change | 34 |
| P-01708 | 26% | S07 | CR-01 | improved | 59 |
| P-01696 | 24% | S20 | CR-01 | improved | 59 |
| P-01835 | 24% | S17 | CR-01 | improved | 56 |
| P-01877 | 24% | S01 | CR-01 | improved | 67 |
| P-01388 | 23% | S17 | CR-01 | improved | 59 |
| P-01371 | 22% | S06 | CR-01 | improved | 63 |
| P-01442 | 21% | S13 | CR-01 | improved | 61 |
| P-01430 | 17% | S05 | CR-01 | improved | 54 |
| P-01342 | 16% | S11 | DT-01 | improved | 48 |