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Patient P-01780

Synthetic patientNBL-101 · Day 110 · 75+ · M · baseline S02Steering view · 3DOpen companion preview
Therapy response
Favorable
Tolerance
Favorable
GI state
Improving
Inflammatory state
Favorable
Nutritional resilience
Improving
Discontinuation risk
15%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 NBL-101 started — Baseline state S02

What changed?

Trajectory is tracking the baseline prediction.

Primary contributors, last 14 days
  • Nutritional resilience+12
  • GI instability-9
  • Treatment adherence-6
  • Toxicity+4
  • Inflammatory activity-3

What helped?

No interventions yet.

    LIFE OS recommendation
    No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

    Daily trackers

    Molecule settings

    The trackers this program marks as important, last 14 days vs the 14 before.

    GI burden
    Companion
    14.9/100
    improving · -11.9 vs previous 14 d
    Toxicity
    Blood
    29.4/100
    improving · -3.5 vs previous 14 d
    Sleep quality
    Wearable
    55.6/100
    improving · +9.5 vs previous 14 d
    Energy level
    Daily log
    5.3/10
    improving · +0.8 vs previous 14 d
    Stress level
    Daily log
    3.4/10
    improving · -0.9 vs previous 14 d
    Steps
    Wearable
    5,520
    improving · +1,077 vs previous 14 d
    Adherence
    Companion
    92 %
    stable · -3.1 vs previous 14 d
    This trajectory is doing well — what to keep, what to watch
    Steering view →

    Heading towards restoration · 76 from the failing basin, 18 from restoration.

    Good elements to keep
    • Butyrate producers intact
      hidden · steering +7.5
    • Daily walks resumed
      perturbation · steering +3.3
    Main detractors to watch
    • Spicy / capsaicin
      perturbation · steering -7.7
    • Bacteroides fragilis elevated
      hidden · steering -7.4
    • IL6 high-expression variant
      hidden · steering -7.3
    • Poor-sleep week
      perturbation · steering -3
    • Spicy / capsaicin
      detractor · GI +4.6 next day
    State influencers · digestive

    Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

    • Spicy / capsaicin
      +4.6detractor · 95%
    • Insoluble fibre
      +1.3no signal · 25%
    • Dietary fat load
      +1.1no signal · 24%
    • Histamine load
      +1no signal · 18%
    • Alcohol
      -0.3no signal · 15%
    • Simple carbohydrates
      0no signal · 15%

    Biological layers

    Which pathways look influenced, and by which layer of this person's biology.

    Pathways under pressure
    • Inflammatory signalling ↓45
      • DNAIL6 -174 variant raises baseline inflammatory tone
      • MicrobiomeBacteroides fragilis expansion
    • Drug metabolism and exposure ↑35
      • DNADPYD *2A → slower clearance
    • Mucosal barrier integrity ↓30
      • MicrobiomeAkkermansia low → thinner mucus layer
    • Butyrate / short-chain fatty acid production ↓25
      • MicrobiomeF. prausnitzii depleted
    DNA
    Fictional pharmacogenomic panel
    • IL6 -174 G/C
      Higher inflammatory tone
    • DPYD *2A heterozygous
      Slower drug clearance
    • CYP2D6 Normal metabolizer
      Expected exposure
    Microbiome
    Shannon diversity 3 · butyrate capacity 79/100
    • Akkermansia muciniphilaLow
    • Faecalibacterium prausnitziiLow
    • Bacteroides fragilisHigh
    • Bifidobacterium longumNormal
    • EnterobacteriaceaeNormal
    Wearable, last 14 days
    daily evolution fed into the runtime
    HRV
    50 ms
    Sleep
    6.7 h
    Steps
    3,809
    Resting HR
    63 bpm
    Daily log: GI score 15, nutritional resilience 71, adherence 92.

    What this patient sees in NostraAI

    The content that steers the trajectory: what to eat, what to do, what to take.

    Open companion preview
    What to eat
    • Keep meals regular; three to four moderate portions spaced through the day
    • Include a cooked vegetable portion with each main meal
    • Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
    • Avoid known triggers for now: fried or oily food, dairy, alcohol
    What to do
    • Log the daily check-in; one line is enough
    • Keep the current walking rhythm
    • Keep the sleep window steady
    • Keep hydration steady: small amounts through the day rather than large volumes at once
    What to take
    • Take the scheduled dose as agreed with your care team
    • No additional supplements this week
    • Fictional demo item: continue vitamin D as before

    284 biologically similar trajectories

    Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

    Sort by similaritySort by interventionSort by outcomeSort by stateSort by response
    PatientSimilarityBaselineInterventionOutcomeResponse today
    P-0180444%S19AD-05improved61
    P-0137734%S11AD-05no change42
    P-0154134%S09AD-05no change43
    P-0148331%S14AD-05no change35
    P-0167929%S12AD-05no change39
    P-0168933%S13BR-03no change50
    P-0132931%S08BR-03improved79
    P-0146831%S06BR-03no change41
    P-0135030%S19BR-03no change34
    P-0131329%S01BR-03improved32
    P-0167729%S05BR-03no change86
    P-0143049%S05CR-01improved54