600 patients66,869 observations120 daysLIVE

Patient P-01784

Synthetic patientNBL-101 · Day 120 · 25–34 · F · baseline S16Open companion preview
Therapy response
Improving
Tolerance
Favorable
GI state
Favorable
Inflammatory state
Improving
Nutritional resilience
Declining
Discontinuation risk
14%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 NBL-101 startedBaseline state S16
  2. Day 17 Trajectory diverged from predictionObserved response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 17.

Primary contributors, last 14 days
  • Inflammatory activity-10
  • Nutritional resilience-6
  • Treatment adherence-5
  • GI instability+2
  • Toxicity-2

What helped?

No interventions yet.

    LIFE OS recommendation
    No intervention is indicated right now. The trajectory is stable relative to similar patients.

    Biological layers

    Which pathways look influenced, and by which layer of this person's biology.

    Pathways under pressure
    • Inflammatory signalling 45
      • DNAIL6 -174 variant raises baseline inflammatory tone
      • MicrobiomeBacteroides fragilis expansion
    • Mucosal barrier integrity 30
      • MicrobiomeAkkermansia low → thinner mucus layer
    • Butyrate / short-chain fatty acid production 25
      • MicrobiomeF. prausnitzii depleted
    • Autonomic recovery 20
      • Wearable3,687 steps/day
    DNA
    Fictional pharmacogenomic panel
    • IL6 -174 G/C
      Higher inflammatory tone
    • CYP2D6 Rapid metabolizer
      Expected exposure
    Microbiome
    Shannon diversity 3.2 · butyrate capacity 62/100
    • Akkermansia muciniphilaLow
    • Faecalibacterium prausnitziiLow
    • Bacteroides fragilisHigh
    • Bifidobacterium longumNormal
    • EnterobacteriaceaeNormal
    Wearable, last 14 days
    daily evolution fed into the runtime
    HRV
    69 ms
    Sleep
    7.5 h
    Steps
    3,997
    Resting HR
    63 bpm
    Daily log: GI score 17, nutritional resilience 63, adherence 92.

    What this patient sees in NostraAI

    The content that steers the trajectory: what to eat, what to do, what to take.

    Open companion preview
    What to eat
    • Keep meals regular; three to four moderate portions spaced through the day
    • Include a cooked vegetable portion with each main meal
    • Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
    • Avoid known triggers for now: fried or oily food, dairy, alcohol
    What to do
    • Log the daily check-in; one line is enough
    • A 15-minute walk after lunch
    • Keep the sleep window steady
    • Keep hydration steady: small amounts through the day rather than large volumes at once
    What to take
    • Take the scheduled dose as agreed with your care team
    • No additional supplements this week
    • Fictional demo item: continue vitamin D as before

    284 biologically similar trajectories

    Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

    PatientSimilarityBaselineInterventionOutcomeResponse today
    P-0176637%S05AD-05no change90
    P-0180426%S19AD-05improved61
    P-0154125%S09AD-05no change43
    P-0167752%S05BR-03no change86
    P-0132937%S08BR-03improved79
    P-0149534%S07BR-03improved85
    P-0168926%S13BR-03no change50
    P-0165433%S08CR-01improved85
    P-0143025%S05CR-01improved54
    P-0147950%S15DT-01improved84
    P-0185544%S04DT-01improved73
    P-0172433%S10DT-01improved63