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Patient P-01784

Synthetic patientNBL-101 · Day 120 · 25–34 · F · baseline S16Steering view · 3DOpen companion preview
Therapy response
Improving
Tolerance
Favorable
GI state
Favorable
Inflammatory state
Improving
Nutritional resilience
Declining
Discontinuation risk
14%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 NBL-101 started — Baseline state S16
  2. Day 17 Trajectory diverged from prediction — Observed response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 17.

Primary contributors, last 14 days
  • Inflammatory activity-10
  • Nutritional resilience-6
  • Treatment adherence-5
  • GI instability+2
  • Toxicity-2

What helped?

No interventions yet.

    LIFE OS recommendation
    No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

    Daily trackers

    Molecule settings

    The trackers this program marks as important, last 14 days vs the 14 before.

    GI burden
    Companion
    16.9/100
    improving · -1.6 vs previous 14 d
    Toxicity
    Blood
    13.6/100
    stable · +0.0 vs previous 14 d
    Sleep quality
    Wearable
    76.8/100
    stable · +2.3 vs previous 14 d
    Energy level
    Daily log
    6.5/10
    stable · +0.1 vs previous 14 d
    Stress level
    Daily log
    4/10
    stable · +0.1 vs previous 14 d
    Steps
    Wearable
    3,687
    improving · +231 vs previous 14 d
    Adherence
    Companion
    92.2 %
    stable · +0.3 vs previous 14 d
    This trajectory is doing well — what to keep, what to watch
    Steering view →

    Heading towards restoration · 93 from the failing basin, 7 from restoration.

    Good elements to keep
    • Butyrate producers intact
      hidden · steering +7.5
    Main detractors to watch
    • Rapid metabolizer
      hidden · steering -8
    • Bacteroides fragilis elevated
      hidden · steering -7.4
    • IL6 high-expression variant
      hidden · steering -7.3
    • Alcohol
      perturbation · steering -5
    • Alcohol
      detractor · GI +3.1 next day
    State influencers · digestive

    Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

    • Alcohol
      +3.1detractor · 71%
    • Spicy / capsaicin
      +2.2no signal · 47%
    • Dietary fat load
      +1.4no signal · 28%
    • Insoluble fibre
      -1no signal · 17%
    • Simple carbohydrates
      -0.2no signal · 15%
    • Histamine load
      +0.1no signal · 15%

    Biological layers

    Which pathways look influenced, and by which layer of this person's biology.

    Pathways under pressure
    • Inflammatory signalling ↓45
      • DNAIL6 -174 variant raises baseline inflammatory tone
      • MicrobiomeBacteroides fragilis expansion
    • Mucosal barrier integrity ↓30
      • MicrobiomeAkkermansia low → thinner mucus layer
    • Butyrate / short-chain fatty acid production ↓25
      • MicrobiomeF. prausnitzii depleted
    • Autonomic recovery ↓20
      • Wearable3,687 steps/day
    DNA
    Fictional pharmacogenomic panel
    • IL6 -174 G/C
      Higher inflammatory tone
    • CYP2D6 Rapid metabolizer
      Expected exposure
    Microbiome
    Shannon diversity 3.2 · butyrate capacity 62/100
    • Akkermansia muciniphilaLow
    • Faecalibacterium prausnitziiLow
    • Bacteroides fragilisHigh
    • Bifidobacterium longumNormal
    • EnterobacteriaceaeNormal
    Wearable, last 14 days
    daily evolution fed into the runtime
    HRV
    69 ms
    Sleep
    7.5 h
    Steps
    3,997
    Resting HR
    63 bpm
    Daily log: GI score 17, nutritional resilience 63, adherence 92.

    What this patient sees in NostraAI

    The content that steers the trajectory: what to eat, what to do, what to take.

    Open companion preview
    What to eat
    • Keep meals regular; three to four moderate portions spaced through the day
    • Include a cooked vegetable portion with each main meal
    • Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
    • Avoid known triggers for now: fried or oily food, dairy, alcohol
    What to do
    • Log the daily check-in; one line is enough
    • A 15-minute walk after lunch
    • Keep the sleep window steady
    • Keep hydration steady: small amounts through the day rather than large volumes at once
    What to take
    • Take the scheduled dose as agreed with your care team
    • No additional supplements this week
    • Fictional demo item: continue vitamin D as before

    284 biologically similar trajectories

    Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

    Sort by similaritySort by interventionSort by outcomeSort by stateSort by response
    PatientSimilarityBaselineInterventionOutcomeResponse today
    P-0147950%S15DT-01improved84
    P-0185544%S04DT-01improved73
    P-0143942%S18ME-01improved79
    P-0162541%S06SC-12improved83
    P-0146740%S09HY-01improved79
    P-0176339%S16ME-01improved100
    P-0150338%S15ME-01improved80
    P-0167138%S04SC-12improved90
    P-0132937%S08BR-03improved79
    P-0179135%S06ME-01improved79
    P-0149534%S07BR-03improved85
    P-0179634%S09SC-12improved86