Patient P-01795
Synthetic patientNBL-101 · Day 117 · 45–54 · M · baseline S06Steering view · 3DOpen companion preview
Therapy response
Improving
Tolerance
Improving
GI state
Improving
Inflammatory state
Improving
Nutritional resilience
Unstable
Discontinuation risk
50%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S06
- Day 82 Trajectory diverged from prediction — Observed response fell below the model's expected path.
What changed?
Trajectory began diverging from predicted response on Day 82.
Primary contributors, last 14 days
- Inflammatory activity-16
- Toxicity-14
- GI instability-10
- Treatment adherence+9
- Nutritional resilience+2
What helped?
No interventions yet.
LIFE OS recommendation
GI Support Protocol GI-04
65%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 85% showed improvement
- median effect visible after 8 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
GI burden
Companion54/100
stable · -0.4 vs previous 14 d
Toxicity
Blood49.8/100
stable · +1.8 vs previous 14 d
Sleep quality
Wearable25.9/100
stable · -1.0 vs previous 14 d
Energy level
Daily log2.8/10
stable · +0.0 vs previous 14 d
Stress level
Daily log6.7/10
stable · -0.1 vs previous 14 d
Steps
Wearable8,069
stable · -237 vs previous 14 d
Adherence
Companion74.3 %
worsening · -4.2 vs previous 14 d
This trajectory is doing well — what to keep, what to watch
Steering view →Heading towards restoration · 45 from the failing basin, 47 from restoration.
Good elements to keep
- Daily walks resumedperturbation · steering +3.3
Main detractors to watch
- Low butyrate capacityhidden · steering -17.5
- FUT2 non-secretorhidden · steering -10.6
- Histamine loadperturbation · steering -9.3
- Dietary fat loadperturbation · steering -8.1
- Histamine loaddetractor · GI +4.8 next day
- Dietary fat loaddetractor · GI +4.4 next day
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Histamine load+4.8detractor · 95%
- Dietary fat load+4.4detractor · 95%
- Spicy / capsaicin+3.5detractor · 95%
- Alcohol-1.8no signal · 45%
- Insoluble fibre-1.4no signal · 35%
- Simple carbohydrates+1.2no signal · 37%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Inflammatory signalling ↓70
- DNAIL6 -174 variant raises baseline inflammatory tone
- MicrobiomeBacteroides fragilis expansion
- BloodInflammatory load index 47
- Butyrate / short-chain fatty acid production ↓55
- MicrobiomeButyrate capacity 25/100
- Daily logFibre intake low in recent food logs
- Mucosal barrier integrity ↓50
- DNAFUT2 non-secretor lowers mucosal fucosylation
- Daily logGI symptom score 54 and rising
- Autonomic recovery ↑45
- WearableResting HR 77 bpm
- WearableShort sleep window
- Drug metabolism and exposure ↑20
- BloodToxicity index 50
DNA
Fictional pharmacogenomic panel
- FUT2 rs601338 AA (non-secretor)Reduced mucosal fucosylation
- IL6 -174 G/CHigher inflammatory tone
- CYP2D6 Intermediate metabolizerExpected exposure
Microbiome
Shannon diversity 2.8 · butyrate capacity 25/100
- Akkermansia muciniphilaNormal
- Faecalibacterium prausnitziiNormal
- Bacteroides fragilisHigh
- Bifidobacterium longumNormal
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 40 ms
- Sleep
- 6.5 h
- Steps
- 6,892
- Resting HR
- 77 bpm
Daily log: GI score 54, nutritional resilience 39, adherence 74.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- Keep the current walking rhythm
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-01699 | 49% | S04 | GI-04 | improved | 69 |
| P-01708 | 44% | S07 | CR-01 | improved | 59 |
| P-01877 | 43% | S01 | CR-01 | improved | 67 |
| P-01696 | 42% | S20 | CR-01 | improved | 59 |
| P-01371 | 41% | S06 | CR-01 | improved | 63 |
| P-01388 | 39% | S17 | CR-01 | improved | 59 |
| P-01835 | 38% | S17 | CR-01 | improved | 56 |
| P-01442 | 37% | S13 | CR-01 | improved | 61 |
| P-01438 | 36% | S14 | GI-04 | improved | 56 |
| P-01433 | 35% | S14 | GI-04 | improved | 48 |
| P-01588 | 34% | S14 | GI-04 | improved | 57 |
| P-01617 | 34% | S14 | SC-12 | improved | 50 |