Patient P-01808
Synthetic patientNBL-101 · Day 110 · 55–64 · F · baseline S10Steering view · 3DOpen companion preview
Therapy response
Unstable
Tolerance
Stable
GI state
Unstable
Inflammatory state
Unstable
Nutritional resilience
Unstable
Discontinuation risk
96%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S10
- Day 47 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 67 ME-01 recommended — Monitoring Escalation ME-01
- Day 68 Patient accepted — Started ME-01 in the companion
- Day 71 Deterioration detected before clinical escalation — Monitoring Escalation ME-01
What changed?
Trajectory began diverging from predicted response on Day 47.
Primary contributors, last 14 days
- GI instability+23
- Inflammatory activity+13
- Nutritional resilience-8
- Toxicity-2
What helped?
- Monitoring Escalation ME-01Day 67Result: deterioration detected before clinical escalation
LIFE OS recommendation
GI Support Protocol GI-04
92%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 83% showed improvement
- median effect visible after 8 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
GI burden
Companion87.9/100
stable · +2.4 vs previous 14 d
Toxicity
Blood50.2/100
worsening · +6.4 vs previous 14 d
Sleep quality
Wearable7.9/100
worsening · -3.1 vs previous 14 d
Energy level
Daily log1.4/10
worsening · -0.5 vs previous 14 d
Stress level
Daily log7.7/10
stable · +0.3 vs previous 14 d
Steps
Wearable6,195
worsening · -273 vs previous 14 d
Adherence
Companion42.2 %
stable · -1.0 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards failing · 25 from the failing basin, 97 from restoration.
Would help
Would not help
- Keep fat lowGI +5.7 next day on high-intake days · n 24
- Keep histamine lowGI +5.7 next day on high-intake days · n 23
- Keep simple carbs lowGI +5.2 next day on high-intake days · n 19
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Dietary fat load+5.7detractor · 95%
- Histamine load+5.7detractor · 95%
- Simple carbohydrates+5.2detractor · 95%
- Alcohol+3.7detractor · 86%
- Insoluble fibre+2.1no signal · 46%
- Spicy / capsaicin+1.9no signal · 35%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Inflammatory signalling ↑85
- DNAIL6 -174 variant raises baseline inflammatory tone
- MicrobiomeBacteroides fragilis expansion
- BloodInflammatory load index 74
- WearableHRV 35 ms, trending down
- Butyrate / short-chain fatty acid production ↓80
- MicrobiomeButyrate capacity 32/100
- MicrobiomeF. prausnitzii depleted
- Daily logFibre intake low in recent food logs
- Mucosal barrier integrity ↓60
- DNAFUT2 non-secretor lowers mucosal fucosylation
- Daily logGI symptom score 88 and rising
- WearableSleep 5.0 h, below personal baseline
- Autonomic recovery ↓45
- WearableResting HR 74 bpm
- WearableShort sleep window
- Drug metabolism and exposure ↑20
- BloodToxicity index 50
DNA
Fictional pharmacogenomic panel
- FUT2 rs601338 AA (non-secretor)Reduced mucosal fucosylation
- IL6 -174 G/CHigher inflammatory tone
- CYP2D6 Normal metabolizerExpected exposure
Microbiome
Shannon diversity 2.9 · butyrate capacity 32/100
- Akkermansia muciniphilaNormal
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisHigh
- Bifidobacterium longumLow
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 37 ms
- Sleep
- 5.4 h
- Steps
- 6,467
- Resting HR
- 70 bpm
Daily log: GI score 88, nutritional resilience 24, adherence 42.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- Keep the current walking rhythm
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-01736 | 44% | S03 | ME-01 | improved | 46 |
| P-01619 | 41% | S14 | GI-04 | worsened | 38 |
| P-01440 | 40% | S12 | GI-04 | no change | 51 |
| P-01728 | 40% | S14 | SC-12 | improved | 41 |
| P-01735 | 40% | S14 | — | — | 40 |
| P-01772 | 40% | S20 | NP-02 | no change | 50 |
| P-01810 | 40% | S05 | NP-02 | improved | 43 |
| P-01854 | 40% | S14 | ME-01 | improved | 46 |
| P-01572 | 39% | S14 | GI-04 | worsened | 41 |
| P-01822 | 39% | S14 | — | — | 37 |
| P-01866 | 39% | S14 | — | — | 40 |
| P-01655 | 38% | S14 | GI-04 | no change | 29 |