Patient P-01809

Synthetic patientNBL-101 · Day 113 · 55–64 · F · baseline S11Steering view · 3D Open companion preview

Therapy response

Improving

Tolerance

Improving

GI state

Favorable

Inflammatory state

Deteriorating

Nutritional resilience

Favorable

Discontinuation risk

13%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 NBL-101 started — Baseline state S11

What changed?

Trajectory is tracking the baseline prediction.

Primary contributors, last 14 days

Inflammatory activity+6
Toxicity-6
Nutritional resilience-3
GI instability-2
Treatment adherence+2

What helped?

No interventions yet.

LIFE OS recommendation

No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

GI burden

Companion

19.7/100

stable · +0.7 vs previous 14 d

Toxicity

Blood

17.6/100

worsening · +0.7 vs previous 14 d

Sleep quality

Wearable

41.7/100

worsening · -3.2 vs previous 14 d

Energy level

Daily log

5.3/10

stable · -0.1 vs previous 14 d

Stress level

Daily log

3.6/10

stable · -0.0 vs previous 14 d

Steps

Wearable

4,511

improving · +404 vs previous 14 d

Adherence

Companion

93.1 %

stable · -1.6 vs previous 14 d

This trajectory is doing well — what to keep, what to watch

Steering view →

Heading towards restoration · 68 from the failing basin, 25 from restoration.

Good elements to keep

Butyrate producers intact
hidden · steering +7.5

Main detractors to watch

Poor metabolizer
hidden · steering -12.7
FUT2 non-secretor
hidden · steering -10.6
Bacteroides fragilis elevated
hidden · steering -7.4
Histamine load
perturbation · steering -6.2
Histamine load
detractor · GI +3.2 next day

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Histamine load
+3.2detractor · 95%
Dietary fat load
+0.7no signal · 22%
Insoluble fibre
+0.3no signal · 15%
Spicy / capsaicin
-0.3no signal · 15%
Simple carbohydrates
-0.1no signal · 15%
Alcohol
+0.1no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Autonomic recovery ↓45
- WearableResting HR 74 bpm
- WearableShort sleep window
Drug metabolism and exposure ↑40
- DNACYP2D6 poor metabolizer → higher exposure
Inflammatory signalling ↑35
- MicrobiomeBacteroides fragilis expansion
- WearableHRV 37 ms, trending down
Mucosal barrier integrity ↓30
- DNAFUT2 non-secretor lowers mucosal fucosylation

DNA

Fictional pharmacogenomic panel

FUT2 rs601338 AA (non-secretor)
Reduced mucosal fucosylation
CYP2D6 Poor metabolizer
Higher exposure at standard dose

Microbiome

Shannon diversity 4.4 · butyrate capacity 52/100

Akkermansia muciniphilaNormal
Faecalibacterium prausnitziiNormal
Bacteroides fragilisHigh
Bifidobacterium longumLow
EnterobacteriaceaeNormal

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 41 ms
Sleep: 6.4 h
Steps: 5,093
Resting HR: 75 bpm

Daily log: GI score 20, nutritional resilience 63, adherence 93.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Keep fibre steady; no new sources this week
Avoid known triggers for now: fried or oily food, dairy, alcohol

What to do

Log the daily check-in; one line is enough
A 15-minute walk after lunch
Protect a 7.5-hour sleep window; screens off 30 minutes before
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the scheduled dose as agreed with your care team
No additional supplements this week
Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-01430	58%	S05	CR-01	improved	54
P-01804	47%	S19	AD-05	improved	61
P-01571	46%	S13	SC-12	improved	57
P-01342	44%	S11	DT-01	improved	48
P-01346	43%	S12	DT-01	improved	52
P-01593	42%	S10	HY-01	improved	56
P-01724	41%	S10	DT-01	improved	63
P-01752	40%	S20	DT-01	improved	50
P-01861	38%	S12	HY-01	improved	47
P-01374	37%	S08	HY-01	improved	49
P-01555	36%	S06	GI-04	improved	56
P-01455	35%	S01	GI-04	improved	61