Patient P-01815

Synthetic patientNBL-101 · Day 117 · 35–44 · M · baseline S09Steering view · 3D Open companion preview

Therapy response

Stable

Tolerance

Deteriorating

GI state

Improving

Inflammatory state

Improving

Nutritional resilience

Favorable

Discontinuation risk

13%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 NBL-101 started — Baseline state S09
Day 82 Trajectory diverged from prediction — Observed response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 82.

Primary contributors, last 14 days

GI instability-15
Inflammatory activity-15
Toxicity+5
Treatment adherence-3
Nutritional resilience+2

What helped?

No interventions yet.

LIFE OS recommendation

No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

GI burden

Companion

10.8/100

improving · -8.9 vs previous 14 d

Toxicity

Blood

25.4/100

improving · -1.1 vs previous 14 d

Sleep quality

Wearable

49.1/100

improving · +9.0 vs previous 14 d

Energy level

Daily log

6/10

improving · +0.6 vs previous 14 d

Stress level

Daily log

4/10

improving · -0.5 vs previous 14 d

Steps

Wearable

4,656

improving · +1,106 vs previous 14 d

Adherence

Companion

87.8 %

stable · -1.1 vs previous 14 d

This trajectory is decaying — what would help, what would not

Steering view →

Heading towards restoration · 83 from the failing basin, 23 from restoration.

Would help

No untried action with strong evidence. Compose one from primitives.

Would not help

Keep histamine low
GI +5.5 next day on high-intake days · n 22
Keep spicy low
GI +4 next day on high-intake days · n 10

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Histamine load
+5.5detractor · 95%
Spicy / capsaicin
+4detractor · 62%
Insoluble fibre
+2no signal · 39%
Simple carbohydrates
+1.8no signal · 32%
Alcohol
+1.2no signal · 22%
Dietary fat load
0no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Mucosal barrier integrity ↓30
- DNAFUT2 non-secretor lowers mucosal fucosylation
Inflammatory signalling ↓15
- WearableHRV 37 ms, trending down

DNA

Fictional pharmacogenomic panel

FUT2 rs601338 AA (non-secretor)
Reduced mucosal fucosylation
CYP2D6 Intermediate metabolizer
Expected exposure
MTHFR C677T
Reduced folate turnover

Microbiome

Shannon diversity 3.3 · butyrate capacity 59/100

Akkermansia muciniphilaNormal
Faecalibacterium prausnitziiNormal
Bacteroides fragilisNormal
Bifidobacterium longumLow
EnterobacteriaceaeNormal

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 36 ms
Sleep: 6.4 h
Steps: 4,296
Resting HR: 73 bpm

Daily log: GI score 11, nutritional resilience 62, adherence 88.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Keep fibre steady; no new sources this week
Avoid known triggers for now: fried or oily food, dairy, alcohol

What to do

Log the daily check-in; one line is enough
A 15-minute walk after lunch
Keep the sleep window steady
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the scheduled dose as agreed with your care team
No additional supplements this week
Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-01804	45%	S19	AD-05	improved	61
P-01541	37%	S09	AD-05	no change	43
P-01377	32%	S11	AD-05	no change	42
P-01483	32%	S14	AD-05	no change	35
P-01679	30%	S12	AD-05	no change	39
P-01468	33%	S06	BR-03	no change	41
P-01350	32%	S19	BR-03	no change	34
P-01689	31%	S13	BR-03	no change	50
P-01329	30%	S08	BR-03	improved	79
P-01313	29%	S01	BR-03	improved	32
P-01430	44%	S05	CR-01	improved	54
P-01654	29%	S08	CR-01	improved	85