Patient P-01824
Synthetic patientNBL-101 · Day 113 · 65–74 · F · baseline S14Steering view · 3DOpen companion preview
Therapy response
Unstable
Tolerance
Improving
GI state
Unstable
Inflammatory state
Unstable
Nutritional resilience
Unstable
Discontinuation risk
96%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S14
- Day 46 Trajectory diverged from prediction — Observed response fell below the model's expected path.
What changed?
Trajectory began diverging from predicted response on Day 46.
Primary contributors, last 14 days
- Treatment adherence-6
- Toxicity-5
- Nutritional resilience-4
- GI instability+3
What helped?
No interventions yet.
LIFE OS recommendation
GI Support Protocol GI-04
91%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 83% showed improvement
- median effect visible after 8 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
GI burden
Companion71.4/100
worsening · +7.8 vs previous 14 d
Toxicity
Blood37.7/100
improving · -7.1 vs previous 14 d
Sleep quality
Wearable11.1/100
worsening · -4.1 vs previous 14 d
Energy level
Daily log1.6/10
worsening · -0.3 vs previous 14 d
Stress level
Daily log6.5/10
stable · +0.0 vs previous 14 d
Steps
Wearable1,837
worsening · -308 vs previous 14 d
Adherence
Companion43.4 %
stable · +1.1 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards failing · 22 from the failing basin, 74 from restoration.
Would help
Would not help
- Keep simple carbs lowGI +5.1 next day on high-intake days · n 18
- Keep histamine lowGI +4.8 next day on high-intake days · n 22
- Keep fat lowGI +4.7 next day on high-intake days · n 19
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Simple carbohydrates+5.1detractor · 95%
- Histamine load+4.8detractor · 95%
- Dietary fat load+4.7detractor · 95%
- Spicy / capsaicin+3.2no signal · 48%
- Insoluble fibre+2.3no signal · 54%
- Alcohol+0.3no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Mucosal barrier integrity ↓90
- DNAFUT2 non-secretor lowers mucosal fucosylation
- MicrobiomeAkkermansia low → thinner mucus layer
- Daily logGI symptom score 71 and rising
- WearableSleep 5.1 h, below personal baseline
- Inflammatory signalling ↑65
- DNAIL6 -174 variant raises baseline inflammatory tone
- BloodInflammatory load index 58
- WearableHRV 28 ms, trending down
- Butyrate / short-chain fatty acid production ↓55
- MicrobiomeButyrate capacity 43/100
- Daily logFibre intake low in recent food logs
- Autonomic recovery ↓40
- Wearable1,837 steps/day
- WearableShort sleep window
DNA
Fictional pharmacogenomic panel
- FUT2 rs601338 AA (non-secretor)Reduced mucosal fucosylation
- IL6 -174 G/CHigher inflammatory tone
- CYP2D6 Rapid metabolizerExpected exposure
Microbiome
Shannon diversity 2.3 · butyrate capacity 43/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiNormal
- Bacteroides fragilisNormal
- Bifidobacterium longumLow
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 28 ms
- Sleep
- 5.2 h
- Steps
- 1,712
- Resting HR
- 70 bpm
Daily log: GI score 71, nutritional resilience 29, adherence 43.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- A 15-minute walk after lunch
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-01377 | 18% | S11 | AD-05 | no change | 42 |
| P-01483 | 18% | S14 | AD-05 | no change | 35 |
| P-01708 | 27% | S07 | CR-01 | improved | 59 |
| P-01696 | 26% | S20 | CR-01 | improved | 59 |
| P-01371 | 25% | S06 | CR-01 | improved | 63 |
| P-01388 | 25% | S17 | CR-01 | improved | 59 |
| P-01835 | 25% | S17 | CR-01 | improved | 56 |
| P-01877 | 25% | S01 | CR-01 | improved | 67 |
| P-01442 | 23% | S13 | CR-01 | improved | 61 |
| P-01430 | 19% | S05 | CR-01 | improved | 54 |
| P-01342 | 18% | S11 | DT-01 | improved | 48 |
| P-01482 | 46% | S14 | GI-04 | improved | 47 |