Patient P-01829

Synthetic patientNBL-101 · Day 114 · 55–64 · M · baseline S11Steering view · 3D Open companion preview

Therapy response

Unstable

Tolerance

Improving

GI state

Favorable

Inflammatory state

Improving

Nutritional resilience

Favorable

Discontinuation risk

14%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 NBL-101 started — Baseline state S11
Day 74 Trajectory diverged from prediction — Observed response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 74.

Primary contributors, last 14 days

Inflammatory activity-6
Toxicity-5
GI instability-2
Treatment adherence-2

What helped?

No interventions yet.

LIFE OS recommendation

No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

GI burden

Companion

15.3/100

improving · -1.5 vs previous 14 d

Toxicity

Blood

16.4/100

improving · -1.2 vs previous 14 d

Sleep quality

Wearable

66.1/100

stable · -1.7 vs previous 14 d

Energy level

Daily log

6.5/10

stable · +0.1 vs previous 14 d

Stress level

Daily log

4/10

improving · -0.2 vs previous 14 d

Steps

Wearable

7,479

stable · +264 vs previous 14 d

Adherence

Companion

84.6 %

stable · +0.7 vs previous 14 d

This trajectory is doing well — what to keep, what to watch

Steering view →

Heading towards restoration · 71 from the failing basin, 47 from restoration.

Good elements to keep

Butyrate producers intact
hidden · steering +7.5
Daily walks resumed
perturbation · steering +3.3

Main detractors to watch

Bacteroides fragilis elevated
hidden · steering -7.4
IL6 high-expression variant
hidden · steering -7.3
Alcohol
perturbation · steering -5.2
Poor-sleep week
perturbation · steering -3
Alcohol
detractor · GI +3.4 next day

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Alcohol
+3.4detractor · 95%
Histamine load
-0.8no signal · 26%
Insoluble fibre
-0.8no signal · 23%
Spicy / capsaicin
+0.3no signal · 15%
Simple carbohydrates
+0.2no signal · 15%
Dietary fat load
+0.1no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Inflammatory signalling ↓45
- DNAIL6 -174 variant raises baseline inflammatory tone
- MicrobiomeBacteroides fragilis expansion
Autonomic recovery ↑25
- WearableResting HR 72 bpm

DNA

Fictional pharmacogenomic panel

IL6 -174 G/C
Higher inflammatory tone
CYP2D6 Normal metabolizer
Expected exposure
MTHFR C677T
Reduced folate turnover

Microbiome

Shannon diversity 4.5 · butyrate capacity 73/100

Akkermansia muciniphilaNormal
Faecalibacterium prausnitziiNormal
Bacteroides fragilisHigh
Bifidobacterium longumLow
EnterobacteriaceaeNormal

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 61 ms
Sleep: 7.9 h
Steps: 7,286
Resting HR: 73 bpm

Daily log: GI score 15, nutritional resilience 65, adherence 85.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Keep fibre steady; no new sources this week
Avoid known triggers for now: fried or oily food, dairy, alcohol

What to do

Log the daily check-in; one line is enough
Keep the current walking rhythm
Keep the sleep window steady
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the scheduled dose as agreed with your care team
No additional supplements this week
Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-01313	48%	S01	BR-03	improved	32
P-01618	42%	S10	GI-04	improved	39
P-01320	41%	S09	HY-01	improved	38
P-01861	38%	S12	HY-01	improved	47
P-01374	37%	S08	HY-01	improved	49
P-01731	37%	S01	ME-01	improved	32
P-01385	35%	S06	HY-01	improved	50
P-01555	35%	S06	GI-04	improved	56
P-01752	34%	S20	DT-01	improved	50
P-01342	33%	S11	DT-01	improved	48
P-01346	33%	S12	DT-01	improved	52
P-01455	32%	S01	GI-04	improved	61