Patient P-01831
Therapy response
Improving
Tolerance
Improving
GI state
Improving
Inflammatory state
Improving
Nutritional resilience
Improving
Discontinuation risk
75%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S15
- Day 46 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 49 SC-12 recommended — Supportive Compound SC-12
- Day 50 Patient accepted — Started SC-12 in the companion
- Day 56 GI symptom burden −23% vs expected — Supportive Compound SC-12
- Day 62 Tolerance state changed — Unstable → Improving
What changed?
Trajectory began diverging from predicted response on Day 46.
Primary contributors, last 14 days
- Inflammatory activity-10
- GI instability-8
- Nutritional resilience+7
- Toxicity-6
- Treatment adherence+3
What helped?
- Supportive Compound SC-12Day 49Result: symptom burden −23%
LIFE OS recommendation
GI Support Protocol GI-04
80%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 84% showed improvement
- median effect visible after 8 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
GI burden
Companion50/100
improving · -2.4 vs previous 14 d
Toxicity
Blood52.4/100
worsening · +4.0 vs previous 14 d
Sleep quality
Wearable23.1/100
stable · +0.9 vs previous 14 d
Energy level
Daily log2.5/10
improving · +0.3 vs previous 14 d
Stress level
Daily log6/10
stable · +0.0 vs previous 14 d
Steps
Wearable1,462
worsening · -166 vs previous 14 d
Adherence
Companion50.8 %
improving · +3.6 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards restoration · 32 from the failing basin, 56 from restoration.
Would help
Would not help
- Keep fat lowGI +3.6 next day on high-intake days · n 21
- Keep spicy lowGI +2.2 next day on high-intake days · n 13
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Dietary fat load+3.6detractor · 95%
- Spicy / capsaicin+2.2detractor · 71%
- Simple carbohydrates+0.8no signal · 26%
- Alcohol-0.8no signal · 25%
- Insoluble fibre+0.2no signal · 15%
- Histamine load+0.1no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Butyrate / short-chain fatty acid production ↓80
- MicrobiomeButyrate capacity 35/100
- MicrobiomeF. prausnitzii depleted
- Daily logFibre intake low in recent food logs
- Inflammatory signalling ↓70
- DNAIL6 -174 variant raises baseline inflammatory tone
- MicrobiomeBacteroides fragilis expansion
- BloodInflammatory load index 57
- Autonomic recovery ↑65
- WearableResting HR 74 bpm
- Wearable1,462 steps/day
- WearableShort sleep window
- Drug metabolism and exposure ↑55
- DNADPYD *2A → slower clearance
- BloodToxicity index 52
- Mucosal barrier integrity ↓30
- Daily logGI symptom score 50 and rising
- WearableSleep 5.6 h, below personal baseline
DNA
Fictional pharmacogenomic panel
- IL6 -174 G/CHigher inflammatory tone
- DPYD *2A heterozygousSlower drug clearance
- CYP2D6 Normal metabolizerExpected exposure
Microbiome
Shannon diversity 3.1 · butyrate capacity 35/100
- Akkermansia muciniphilaNormal
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisHigh
- Bifidobacterium longumLow
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 52 ms
- Sleep
- 5.7 h
- Steps
- 1,983
- Resting HR
- 77 bpm
Daily log: GI score 50, nutritional resilience 43, adherence 51.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- A 15-minute walk after lunch
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-01581 | 59% | S18 | GI-04 | improved | 51 |
| P-01389 | 51% | S14 | SC-12 | improved | 46 |
| P-01413 | 49% | S14 | GI-04 | improved | 44 |
| P-01544 | 49% | S15 | GI-04 | improved | 50 |
| P-01716 | 49% | S14 | GI-04 | improved | 56 |
| P-01307 | 48% | S14 | GI-04 | improved | 43 |
| P-01365 | 48% | S14 | SC-12 | improved | 49 |
| P-01436 | 48% | S14 | GI-04 | improved | 38 |
| P-01598 | 48% | S14 | GI-04 | no change | 45 |
| P-01707 | 48% | S14 | GI-04 | improved | 57 |
| P-01842 | 48% | S14 | NP-02 | improved | 55 |
| P-01473 | 47% | S14 | GI-04 | improved | 51 |