Patient P-01833
Therapy response
Improving
Tolerance
Improving
GI state
Unstable
Inflammatory state
Unstable
Nutritional resilience
Unstable
Discontinuation risk
93%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S14
- Day 45 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 70 ME-01 recommended — Monitoring Escalation ME-01
- Day 71 Patient accepted — Started ME-01 in the companion
- Day 74 Deterioration detected before clinical escalation — Monitoring Escalation ME-01
What changed?
Trajectory began diverging from predicted response on Day 45.
Primary contributors, last 14 days
- Toxicity-27
- Inflammatory activity-6
- Nutritional resilience+6
- Treatment adherence+6
What helped?
- Monitoring Escalation ME-01Day 70Result: deterioration detected before clinical escalation
LIFE OS recommendation
GI Support Protocol GI-04
92%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 83% showed improvement
- median effect visible after 8 days
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Inflammatory signalling ↓85
- DNAIL6 -174 variant raises baseline inflammatory tone
- MicrobiomeBacteroides fragilis expansion
- BloodInflammatory load index 59
- WearableHRV 22 ms, trending down
- Butyrate / short-chain fatty acid production ↓80
- MicrobiomeButyrate capacity 43/100
- MicrobiomeF. prausnitzii depleted
- Daily logFibre intake low in recent food logs
- Autonomic recovery ↑25
- WearableResting HR 82 bpm
- Mucosal barrier integrity ↓20
- Daily logGI symptom score 69 and rising
DNA
Fictional pharmacogenomic panel
- IL6 -174 G/CHigher inflammatory tone
- CYP2D6 Intermediate metabolizerExpected exposure
Microbiome
Shannon diversity 1.8 · butyrate capacity 43/100
- Akkermansia muciniphilaNormal
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisHigh
- Bifidobacterium longumLow
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 21 ms
- Sleep
- 6.5 h
- Steps
- 6,945
- Resting HR
- 83 bpm
Daily log: GI score 69, nutritional resilience 39, adherence 40.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- Keep the current walking rhythm
- Keep the sleep window steady
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-01708 | 28% | S07 | CR-01 | improved | 59 |
| P-01877 | 27% | S01 | CR-01 | improved | 67 |
| P-01371 | 26% | S06 | CR-01 | improved | 63 |
| P-01696 | 26% | S20 | CR-01 | improved | 59 |
| P-01835 | 26% | S17 | CR-01 | improved | 56 |
| P-01388 | 25% | S17 | CR-01 | improved | 59 |
| P-01442 | 23% | S13 | CR-01 | improved | 61 |
| P-01430 | 19% | S05 | CR-01 | improved | 54 |
| P-01342 | 18% | S11 | DT-01 | improved | 48 |
| P-01595 | 46% | S14 | GI-04 | no change | 51 |
| P-01482 | 45% | S14 | GI-04 | improved | 47 |
| P-01454 | 44% | S14 | GI-04 | no change | 49 |