Patient P-01848

Synthetic patientNBL-101 · Day 113 · 65–74 · F · baseline S05Steering view · 3D Open companion preview

Therapy response

Unstable

Tolerance

Favorable

GI state

Improving

Inflammatory state

Improving

Nutritional resilience

Improving

Discontinuation risk

15%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 NBL-101 started — Baseline state S05
Day 72 AD-05 recommended — Adherence Support AD-05
Day 73 Patient accepted — Started AD-05 in the companion
Day 78 No meaningful change — Adherence Support AD-05
Day 86 Trajectory diverged from prediction — Observed response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 86.

Primary contributors, last 14 days

GI instability-13
Nutritional resilience+12
Inflammatory activity-9
Treatment adherence-3
Toxicity-3

What helped?

Adherence Support AD-05Day 72
Result: no meaningful change

LIFE OS recommendation

No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

GI burden

Companion

12.2/100

improving · -4.3 vs previous 14 d

Toxicity

Blood

22.8/100

improving · -5.2 vs previous 14 d

Sleep quality

Wearable

74.6/100

stable · +2.0 vs previous 14 d

Energy level

Daily log

5.9/10

improving · +0.3 vs previous 14 d

Stress level

Daily log

2.8/10

improving · -0.5 vs previous 14 d

Steps

Wearable

5,643

improving · +532 vs previous 14 d

Adherence

Companion

81.1 %

worsening · -3.7 vs previous 14 d

This trajectory is doing well — what to keep, what to watch

Steering view →

Heading towards restoration · 72 from the failing basin, 56 from restoration.

Good elements to keep

Butyrate producers intact
hidden · steering +7.5
Adherence Support AD-05
intervention · steering +1.4

Main detractors to watch

Bacteroides fragilis elevated
hidden · steering -7.4
Poor-sleep week
perturbation · steering -3
Low-HRV stretch
perturbation · steering -2.7
Dietary drift
perturbation · steering -2.6

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Spicy / capsaicin
+1.5no signal · 31%
Simple carbohydrates
+0.9no signal · 15%
Insoluble fibre
-0.7no signal · 15%
Dietary fat load
-0.5no signal · 15%
Histamine load
-0.1no signal · 15%
Alcohol
0no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Mucosal barrier integrity ↓30
- MicrobiomeAkkermansia low → thinner mucus layer
Inflammatory signalling ↓20
- MicrobiomeBacteroides fragilis expansion

DNA

Fictional pharmacogenomic panel

CYP2D6 Normal metabolizer
Expected exposure
MTHFR C677T
Reduced folate turnover

Microbiome

Shannon diversity 3.8 · butyrate capacity 66/100

Akkermansia muciniphilaLow
Faecalibacterium prausnitziiNormal
Bacteroides fragilisHigh
Bifidobacterium longumNormal
EnterobacteriaceaeHigh

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 54 ms
Sleep: 7.8 h
Steps: 5,744
Resting HR: 67 bpm

Daily log: GI score 12, nutritional resilience 72, adherence 81.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Keep fibre steady; no new sources this week
Avoid known triggers for now: fried or oily food, dairy, alcohol

What to do

Log the daily check-in; one line is enough
Keep the current walking rhythm
Keep the sleep window steady
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the scheduled dose as agreed with your care team
No additional supplements this week
Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-01679	41%	S12	AD-05	no change	39
P-01483	35%	S14	AD-05	no change	35
P-01377	34%	S11	AD-05	no change	42
P-01773	33%	S05	AD-05	improved	27
P-01541	32%	S09	AD-05	no change	43
P-01804	23%	S19	AD-05	improved	61
P-01350	41%	S19	BR-03	no change	34
P-01450	37%	S09	BR-03	no change	36
P-01313	35%	S01	BR-03	improved	32
P-01468	33%	S06	BR-03	no change	41
P-01689	28%	S13	BR-03	no change	50
P-01430	25%	S05	CR-01	improved	54