Patient P-01864

Synthetic patientNBL-101 · Day 114 · 55–64 · F · baseline S18Steering view · 3D Open companion preview

Therapy response

Unstable

Tolerance

Favorable

GI state

Deteriorating

Inflammatory state

Deteriorating

Nutritional resilience

Declining

Discontinuation risk

43%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 NBL-101 started — Baseline state S18
Day 24 Trajectory diverged from prediction — Observed response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 24.

Primary contributors, last 14 days

GI instability+17
Inflammatory activity+15
Nutritional resilience-15
Toxicity+2

What helped?

No interventions yet.

LIFE OS recommendation

No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

GI burden

Companion

27.7/100

worsening · +4.8 vs previous 14 d

Toxicity

Blood

22.4/100

improving · -1.2 vs previous 14 d

Sleep quality

Wearable

24.4/100

worsening · -5.8 vs previous 14 d

Energy level

Daily log

5.1/10

stable · +0.2 vs previous 14 d

Stress level

Daily log

4.3/10

stable · +0.2 vs previous 14 d

Steps

Wearable

4,091

worsening · -488 vs previous 14 d

Adherence

Companion

84.1 %

stable · +1.5 vs previous 14 d

This trajectory is decaying — what would help, what would not

Steering view →

Heading towards failing · 54 from the failing basin, 47 from restoration.

Would help

No untried action with strong evidence. Compose one from primitives.

Would not help

Keep histamine low
GI +4.9 next day on high-intake days · n 22

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Histamine load
+4.9detractor · 95%
Dietary fat load
-1.9no signal · 47%
Simple carbohydrates
-1.5no signal · 34%
Spicy / capsaicin
-1no signal · 20%
Alcohol
+0.8no signal · 18%
Insoluble fibre
+0.7no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Mucosal barrier integrity ↓40
- DNAFUT2 non-secretor lowers mucosal fucosylation
- WearableSleep 5.7 h, below personal baseline
Autonomic recovery ↓20
- WearableShort sleep window
Inflammatory signalling ↑15
- WearableHRV 35 ms, trending down

DNA

Fictional pharmacogenomic panel

FUT2 rs601338 AA (non-secretor)
Reduced mucosal fucosylation
CYP2D6 Rapid metabolizer
Expected exposure
MTHFR C677T
Reduced folate turnover

Microbiome

Shannon diversity 3.2 · butyrate capacity 79/100

Akkermansia muciniphilaNormal
Faecalibacterium prausnitziiNormal
Bacteroides fragilisNormal
Bifidobacterium longumLow
EnterobacteriaceaeHigh

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 32 ms
Sleep: 6.3 h
Steps: 5,675
Resting HR: 68 bpm

Daily log: GI score 28, nutritional resilience 56, adherence 84.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Keep fibre steady; no new sources this week
Avoid known triggers for now: fried or oily food, dairy, alcohol

What to do

Log the daily check-in; one line is enough
A 15-minute walk after lunch
Protect a 7.5-hour sleep window; screens off 30 minutes before
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the scheduled dose as agreed with your care team
No additional supplements this week
Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-01773	42%	S05	AD-05	improved	27
P-01731	39%	S01	ME-01	improved	32
P-01313	31%	S01	BR-03	improved	32
P-01342	31%	S11	DT-01	improved	48
P-01346	30%	S12	DT-01	improved	52
P-01593	30%	S10	HY-01	improved	56
P-01752	30%	S20	DT-01	improved	50
P-01320	29%	S09	HY-01	improved	38
P-01374	29%	S08	HY-01	improved	49
P-01383	29%	S14	NP-02	improved	40
P-01430	29%	S05	CR-01	improved	54
P-01618	29%	S10	GI-04	improved	39