600 patients66,869 observations120 daysLIVE

Patient P-01864

Synthetic patientNBL-101 · Day 114 · 55–64 · F · baseline S18Steering view · 3DOpen companion preview
Therapy response
Unstable
Tolerance
Favorable
GI state
Deteriorating
Inflammatory state
Deteriorating
Nutritional resilience
Declining
Discontinuation risk
43%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 NBL-101 startedBaseline state S18
  2. Day 24 Trajectory diverged from predictionObserved response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 24.

Primary contributors, last 14 days
  • GI instability+17
  • Inflammatory activity+15
  • Nutritional resilience-15
  • Toxicity+2

What helped?

No interventions yet.

    LIFE OS recommendation
    No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

    Daily trackers

    Molecule settings

    The trackers this program marks as important, last 14 days vs the 14 before.

    GI burden
    Companion
    27.7/100
    worsening · +4.8 vs previous 14 d
    Toxicity
    Blood
    22.4/100
    improving · -1.2 vs previous 14 d
    Sleep quality
    Wearable
    24.4/100
    worsening · -5.8 vs previous 14 d
    Energy level
    Daily log
    5.1/10
    stable · +0.2 vs previous 14 d
    Stress level
    Daily log
    4.3/10
    stable · +0.2 vs previous 14 d
    Steps
    Wearable
    4,091
    worsening · -488 vs previous 14 d
    Adherence
    Companion
    84.1 %
    stable · +1.5 vs previous 14 d
    This trajectory is decaying — what would help, what would not
    Steering view →

    Heading towards failing · 54 from the failing basin, 47 from restoration.

    Would help
    • No untried action with strong evidence. Compose one from primitives.
    Would not help
    • Keep histamine low
      GI +4.9 next day on high-intake days · n 22
    State influencers · digestive

    Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

    • Histamine load
      +4.9detractor · 95%
    • Dietary fat load
      -1.9no signal · 47%
    • Simple carbohydrates
      -1.5no signal · 34%
    • Spicy / capsaicin
      -1no signal · 20%
    • Alcohol
      +0.8no signal · 18%
    • Insoluble fibre
      +0.7no signal · 15%

    Biological layers

    Which pathways look influenced, and by which layer of this person's biology.

    Pathways under pressure
    • Mucosal barrier integrity 40
      • DNAFUT2 non-secretor lowers mucosal fucosylation
      • WearableSleep 5.7 h, below personal baseline
    • Autonomic recovery 20
      • WearableShort sleep window
    • Inflammatory signalling 15
      • WearableHRV 35 ms, trending down
    DNA
    Fictional pharmacogenomic panel
    • FUT2 rs601338 AA (non-secretor)
      Reduced mucosal fucosylation
    • CYP2D6 Rapid metabolizer
      Expected exposure
    • MTHFR C677T
      Reduced folate turnover
    Microbiome
    Shannon diversity 3.2 · butyrate capacity 79/100
    • Akkermansia muciniphilaNormal
    • Faecalibacterium prausnitziiNormal
    • Bacteroides fragilisNormal
    • Bifidobacterium longumLow
    • EnterobacteriaceaeHigh
    Wearable, last 14 days
    daily evolution fed into the runtime
    HRV
    32 ms
    Sleep
    6.3 h
    Steps
    5,675
    Resting HR
    68 bpm
    Daily log: GI score 28, nutritional resilience 56, adherence 84.

    What this patient sees in NostraAI

    The content that steers the trajectory: what to eat, what to do, what to take.

    Open companion preview
    What to eat
    • Keep meals regular; three to four moderate portions spaced through the day
    • Include a cooked vegetable portion with each main meal
    • Keep fibre steady; no new sources this week
    • Avoid known triggers for now: fried or oily food, dairy, alcohol
    What to do
    • Log the daily check-in; one line is enough
    • A 15-minute walk after lunch
    • Protect a 7.5-hour sleep window; screens off 30 minutes before
    • Keep hydration steady: small amounts through the day rather than large volumes at once
    What to take
    • Take the scheduled dose as agreed with your care team
    • No additional supplements this week
    • Fictional demo item: continue vitamin D as before

    284 biologically similar trajectories

    Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

    PatientSimilarityBaselineInterventionOutcomeResponse today
    P-0169540%S0130
    P-0173139%S01ME-01improved32
    P-0134738%S0125
    P-0184633%S0137
    P-0181632%S0135
    P-0131331%S01BR-03improved32
    P-0184731%S0137
    P-0182329%S0157
    P-0170327%S0151
    P-0145526%S01GI-04improved61
    P-0160425%S0171
    P-0182125%S0158