Patient P-01868
Synthetic patientNBL-101 · Day 112 · 55–64 · M · baseline S14Steering view · 3DOpen companion preview
Therapy response
Improving
Tolerance
Stable
GI state
Improving
Inflammatory state
Improving
Nutritional resilience
Unstable
Discontinuation risk
90%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S14
- Day 48 Trajectory diverged from prediction — Observed response fell below the model's expected path.
What changed?
Trajectory began diverging from predicted response on Day 48.
Primary contributors, last 14 days
- GI instability-20
- Nutritional resilience+15
- Inflammatory activity-12
- Treatment adherence-6
- Toxicity+2
What helped?
No interventions yet.
LIFE OS recommendation
GI Support Protocol GI-04
92%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 84% showed improvement
- median effect visible after 8 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
GI burden
Companion50.7/100
improving · -10.8 vs previous 14 d
Toxicity
Blood55.9/100
worsening · +2.4 vs previous 14 d
Sleep quality
Wearable24.8/100
improving · +3.3 vs previous 14 d
Energy level
Daily log3.3/10
improving · +0.6 vs previous 14 d
Stress level
Daily log6.5/10
improving · -0.5 vs previous 14 d
Steps
Wearable5,056
improving · +915 vs previous 14 d
Adherence
Companion42 %
stable · +0.6 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards restoration · 32 from the failing basin, 55 from restoration.
Would help
Would not help
- Keep fat lowGI +5.9 next day on high-intake days · n 15
- Keep simple carbs lowGI +4.9 next day on high-intake days · n 15
- Keep spicy lowGI +3.8 next day on high-intake days · n 14
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Dietary fat load+5.9detractor · 95%
- Simple carbohydrates+4.9detractor · 86%
- Spicy / capsaicin+3.8detractor · 59%
- Histamine load-2.3no signal · 43%
- Alcohol+1.9no signal · 34%
- Insoluble fibre+1.1no signal · 18%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Inflammatory signalling ↓85
- DNAIL6 -174 variant raises baseline inflammatory tone
- MicrobiomeBacteroides fragilis expansion
- BloodInflammatory load index 53
- WearableHRV 29 ms, trending down
- Butyrate / short-chain fatty acid production ↓55
- MicrobiomeButyrate capacity 24/100
- Daily logFibre intake low in recent food logs
- Mucosal barrier integrity ↓50
- MicrobiomeAkkermansia low → thinner mucus layer
- Daily logGI symptom score 51 and rising
- Drug metabolism and exposure ↑20
- BloodToxicity index 56
- Autonomic recovery ↑20
- WearableShort sleep window
DNA
Fictional pharmacogenomic panel
- IL6 -174 G/CHigher inflammatory tone
- CYP2D6 Normal metabolizerExpected exposure
Microbiome
Shannon diversity 1.9 · butyrate capacity 24/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiNormal
- Bacteroides fragilisHigh
- Bifidobacterium longumNormal
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 31 ms
- Sleep
- 5.6 h
- Steps
- 4,033
- Resting HR
- 67 bpm
Daily log: GI score 51, nutritional resilience 42, adherence 42.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- Keep the current walking rhythm
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-01564 | 48% | S14 | ME-01 | improved | 39 |
| P-01751 | 48% | S14 | ME-01 | improved | 48 |
| P-01605 | 46% | S14 | ME-01 | improved | 41 |
| P-01311 | 45% | S14 | ME-01 | improved | 49 |
| P-01732 | 44% | S14 | ME-01 | improved | 45 |
| P-01656 | 42% | S14 | ME-01 | improved | 41 |
| P-01492 | 41% | S15 | ME-01 | improved | 44 |
| P-01834 | 41% | S14 | NP-02 | improved | 44 |
| P-01897 | 41% | S14 | ME-01 | improved | 43 |
| P-01573 | 40% | S14 | GI-04 | improved | 49 |
| P-01364 | 39% | S14 | GI-04 | improved | 49 |
| P-01394 | 39% | S05 | SC-12 | improved | 44 |