Patient P-01872
Synthetic patientNBL-101 · Day 104 · 45–54 · M · baseline S14Steering view · 3DOpen companion preview
Therapy response
Stable
Tolerance
Stable
GI state
Unstable
Inflammatory state
Improving
Nutritional resilience
Unstable
Discontinuation risk
91%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S14
- Day 31 NP-02 recommended — Dietary Support Protocol NP-02
- Day 32 Patient accepted — Started NP-02 in the companion
- Day 42 GI symptom burden −14% vs expected — Dietary Support Protocol NP-02
- Day 48 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 48 Tolerance state changed — Unstable → Improving
What changed?
Trajectory began diverging from predicted response on Day 48.
Primary contributors, last 14 days
- Inflammatory activity-6
- Treatment adherence+3
What helped?
- Dietary Support Protocol NP-02Day 31Result: symptom burden −14%
LIFE OS recommendation
GI Support Protocol GI-04
92%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 83% showed improvement
- median effect visible after 8 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
GI burden
Companion64.4/100
stable · -0.7 vs previous 14 d
Toxicity
Blood46.1/100
worsening · +3.2 vs previous 14 d
Sleep quality
Wearable15.6/100
stable · +0.5 vs previous 14 d
Energy level
Daily log1.8/10
worsening · -0.4 vs previous 14 d
Stress level
Daily log8.2/10
stable · +0.2 vs previous 14 d
Steps
Wearable6,065
improving · +240 vs previous 14 d
Adherence
Companion49.8 %
stable · +0.2 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards restoration · 28 from the failing basin, 64 from restoration.
Would help
Would not help
- Keep fat lowGI +5.1 next day on high-intake days · n 28
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Dietary fat load+5.1detractor · 95%
- Spicy / capsaicin+1.6no signal · 33%
- Histamine load+1.4no signal · 27%
- Insoluble fibre-1.2no signal · 31%
- Simple carbohydrates+0.7no signal · 15%
- Alcohol-0.7no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Inflammatory signalling ↓85
- DNAIL6 -174 variant raises baseline inflammatory tone
- MicrobiomeBacteroides fragilis expansion
- BloodInflammatory load index 53
- WearableHRV 23 ms, trending down
- Butyrate / short-chain fatty acid production ↓80
- MicrobiomeButyrate capacity 35/100
- MicrobiomeF. prausnitzii depleted
- Daily logFibre intake low in recent food logs
- Mucosal barrier integrity ↓60
- MicrobiomeAkkermansia low → thinner mucus layer
- Daily logGI symptom score 64 and rising
- WearableSleep 5.6 h, below personal baseline
- Autonomic recovery ↑45
- WearableResting HR 75 bpm
- WearableShort sleep window
- Drug metabolism and exposure ↑20
- BloodToxicity index 46
DNA
Fictional pharmacogenomic panel
- IL6 -174 G/CHigher inflammatory tone
- CYP2D6 Rapid metabolizerExpected exposure
Microbiome
Shannon diversity 3 · butyrate capacity 35/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisHigh
- Bifidobacterium longumLow
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 20 ms
- Sleep
- 5.8 h
- Steps
- 5,555
- Resting HR
- 74 bpm
Daily log: GI score 64, nutritional resilience 34, adherence 50.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- Keep the current walking rhythm
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-01813 | 45% | S01 | NP-02 | no change | 40 |
| P-01327 | 44% | S01 | GI-04 | improved | 56 |
| P-01688 | 37% | S01 | GI-04 | improved | 40 |
| P-01310 | 33% | S01 | — | — | 57 |
| P-01877 | 28% | S01 | CR-01 | improved | 67 |
| P-01821 | 21% | S01 | — | — | 58 |
| P-01823 | 21% | S01 | — | — | 57 |
| P-01604 | 20% | S01 | — | — | 71 |
| P-01846 | 20% | S01 | — | — | 37 |
| P-01635 | 38% | S02 | GI-04 | improved | 49 |
| P-01452 | 37% | S02 | GI-04 | improved | 46 |
| P-01459 | 29% | S02 | — | — | 51 |