Patient P-01875

Synthetic patientNBL-101 · Day 91 · 35–44 · M · baseline S11Steering view · 3D Open companion preview

Therapy response

Improving

Tolerance

Favorable

GI state

Deteriorating

Inflammatory state

Deteriorating

Nutritional resilience

Declining

Discontinuation risk

25%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 NBL-101 started — Baseline state S11
Day 15 Trajectory diverged from prediction — Observed response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 15.

Primary contributors, last 14 days

Inflammatory activity+8
GI instability+5
Nutritional resilience-5
Treatment adherence+5

What helped?

No interventions yet.

LIFE OS recommendation

No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

GI burden

Companion

23.2/100

improving · -3.2 vs previous 14 d

Toxicity

Blood

22.2/100

improving · -3.9 vs previous 14 d

Sleep quality

Wearable

63.2/100

improving · +6.5 vs previous 14 d

Energy level

Daily log

5.9/10

improving · +0.7 vs previous 14 d

Stress level

Daily log

3.6/10

improving · -0.3 vs previous 14 d

Steps

Wearable

8,890

stable · +184 vs previous 14 d

Adherence

Companion

89.4 %

stable · -0.6 vs previous 14 d

This trajectory is doing well — what to keep, what to watch

Steering view →

Heading towards restoration · 73 from the failing basin, 14 from restoration.

Good elements to keep

Butyrate producers intact
hidden · steering +7.5

Main detractors to watch

Bacteroides fragilis elevated
hidden · steering -7.4
Antibiotic course
perturbation · steering -4.7
Poor-sleep week
perturbation · steering -3
Dietary drift
perturbation · steering -2.6
Histamine load
detractor · GI +1.3 next day

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Histamine load
+1.3detractor · 66%
Spicy / capsaicin
+0.8no signal · 31%
Insoluble fibre
-0.6no signal · 25%
Dietary fat load
+0.5no signal · 22%
Simple carbohydrates
-0.3no signal · 15%
Alcohol
-0.3no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Mucosal barrier integrity ↓30
- MicrobiomeAkkermansia low → thinner mucus layer
Butyrate / short-chain fatty acid production ↓25
- MicrobiomeF. prausnitzii depleted
Inflammatory signalling ↑20
- MicrobiomeBacteroides fragilis expansion

DNA

Fictional pharmacogenomic panel

CYP2D6 Normal metabolizer
Expected exposure

Microbiome

Shannon diversity 3.4 · butyrate capacity 72/100

Akkermansia muciniphilaLow
Faecalibacterium prausnitziiLow
Bacteroides fragilisHigh
Bifidobacterium longumNormal
EnterobacteriaceaeNormal

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 56 ms
Sleep: 6.8 h
Steps: 8,208
Resting HR: 71 bpm

Daily log: GI score 23, nutritional resilience 65, adherence 89.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
Avoid known triggers for now: fried or oily food, dairy, alcohol

What to do

Log the daily check-in; one line is enough
Keep the current walking rhythm
Keep the sleep window steady
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the scheduled dose as agreed with your care team
No additional supplements this week
Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-01804	38%	S19	AD-05	improved	61
P-01377	34%	S11	AD-05	no change	42
P-01541	33%	S09	AD-05	no change	43
P-01483	30%	S14	AD-05	no change	35
P-01689	35%	S13	BR-03	no change	50
P-01677	31%	S05	BR-03	no change	86
P-01329	30%	S08	BR-03	improved	79
P-01313	28%	S01	BR-03	improved	32
P-01350	28%	S19	BR-03	no change	34
P-01468	28%	S06	BR-03	no change	41
P-01430	39%	S05	CR-01	improved	54
P-01767	48%	S14	DT-01	no change	63