Patient P-01877
Synthetic patientNBL-101 · Day 118 · 35–44 · M · baseline S01Steering view · 3DOpen companion preview
Therapy response
Favorable
Tolerance
Improving
GI state
Unstable
Inflammatory state
Stable
Nutritional resilience
Unstable
Discontinuation risk
89%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S01
- Day 79 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 82 CR-01 recommended — Clinician Review CR-01
- Day 83 Patient accepted — Started CR-01 in the companion
- Day 88 Deterioration detected before clinical escalation — Clinician Review CR-01
What changed?
Trajectory began diverging from predicted response on Day 79.
Primary contributors, last 14 days
- GI instability+24
- Toxicity-9
- Nutritional resilience-8
- Inflammatory activity+4
- Treatment adherence-3
What helped?
- Clinician Review CR-01Day 82Result: deterioration detected before clinical escalation
LIFE OS recommendation
GI Support Protocol GI-04
63%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 83% showed improvement
- median effect visible after 8 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
GI burden
Companion71.7/100
stable · +1.7 vs previous 14 d
Toxicity
Blood44.1/100
improving · -6.3 vs previous 14 d
Sleep quality
Wearable0.9/100
worsening · -4.2 vs previous 14 d
Energy level
Daily log2.2/10
improving · +0.3 vs previous 14 d
Stress level
Daily log6.9/10
stable · -0.1 vs previous 14 d
Steps
Wearable3,499
worsening · -318 vs previous 14 d
Adherence
Companion67.5 %
worsening · -13.4 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards failing · 45 from the failing basin, 66 from restoration.
Would help
Would not help
- Keep simple carbs lowGI +5.2 next day on high-intake days · n 21
- Keep alcohol lowGI +5.1 next day on high-intake days · n 18
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Simple carbohydrates+5.2detractor · 95%
- Alcohol+5.1detractor · 95%
- Insoluble fibre-2.5no signal · 50%
- Spicy / capsaicin+2no signal · 30%
- Histamine load-1.1no signal · 21%
- Dietary fat load-0.6no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Inflammatory signalling ↑65
- DNAIL6 -174 variant raises baseline inflammatory tone
- BloodInflammatory load index 58
- WearableHRV 26 ms, trending down
- Mucosal barrier integrity ↓60
- MicrobiomeAkkermansia low → thinner mucus layer
- Daily logGI symptom score 72 and rising
- WearableSleep 4.2 h, below personal baseline
- Autonomic recovery ↓40
- Wearable3,499 steps/day
- WearableShort sleep window
- Butyrate / short-chain fatty acid production ↓20
- Daily logFibre intake low in recent food logs
- Drug metabolism and exposure ↑20
- BloodToxicity index 44
DNA
Fictional pharmacogenomic panel
- IL6 -174 G/CHigher inflammatory tone
- CYP2D6 Normal metabolizerExpected exposure
- MTHFR C677TReduced folate turnover
Microbiome
Shannon diversity 2.3 · butyrate capacity 48/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiNormal
- Bacteroides fragilisNormal
- Bifidobacterium longumNormal
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 29 ms
- Sleep
- 5.5 h
- Steps
- 3,616
- Resting HR
- 69 bpm
Daily log: GI score 72, nutritional resilience 35, adherence 68.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- A 15-minute walk after lunch
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-01804 | 21% | S19 | AD-05 | improved | 61 |
| P-01388 | 41% | S17 | CR-01 | improved | 59 |
| P-01835 | 40% | S17 | CR-01 | improved | 56 |
| P-01696 | 37% | S20 | CR-01 | improved | 59 |
| P-01708 | 37% | S07 | CR-01 | improved | 59 |
| P-01371 | 35% | S06 | CR-01 | improved | 63 |
| P-01442 | 33% | S13 | CR-01 | improved | 61 |
| P-01430 | 21% | S05 | CR-01 | improved | 54 |
| P-01342 | 21% | S11 | DT-01 | improved | 48 |
| P-01767 | 21% | S14 | DT-01 | no change | 63 |
| P-01699 | 40% | S04 | GI-04 | improved | 69 |
| P-01725 | 34% | S18 | GI-04 | no change | 56 |