Patient P-01884
Synthetic patientNBL-101 · Day 108 · 55–64 · M · baseline S19Steering view · 3DOpen companion preview
Therapy response
Stable
Tolerance
Favorable
GI state
Deteriorating
Inflammatory state
Deteriorating
Nutritional resilience
Declining
Discontinuation risk
53%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S19
- Day 12 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 14 GI-04 recommended — GI Support Protocol GI-04
- Day 15 Patient accepted — Started GI-04 in the companion
- Day 23 No meaningful change — GI Support Protocol GI-04
What changed?
Trajectory began diverging from predicted response on Day 12.
Primary contributors, last 14 days
- GI instability+29
- Inflammatory activity+20
- Nutritional resilience-16
- Treatment adherence+4
- Toxicity-2
What helped?
- GI Support Protocol GI-04Day 14Result: no meaningful change
LIFE OS recommendation
Clinician Review CR-01
72%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 100% showed improvement
- median effect visible after 5 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
GI burden
Companion30.3/100
worsening · +1.6 vs previous 14 d
Toxicity
Blood19.3/100
improving · -9.9 vs previous 14 d
Sleep quality
Wearable28.9/100
improving · +1.7 vs previous 14 d
Energy level
Daily log4.8/10
stable · +0.1 vs previous 14 d
Stress level
Daily log5.9/10
stable · +0.0 vs previous 14 d
Steps
Wearable2,436
improving · +381 vs previous 14 d
Adherence
Companion96.8 %
stable · -2.9 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards failing · 59 from the failing basin, 30 from restoration.
Would help
- ME-01 Monitoring Escalation100% improved among 10 similar · onset 3 d · confidence 60%
Would not help
- GI-04 GI Support Protocolalready tried, no meaningful change
- Keep histamine lowGI +7.4 next day on high-intake days · n 23
- Keep simple carbs lowGI +5.9 next day on high-intake days · n 19
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Histamine load+7.4detractor · 95%
- Simple carbohydrates+5.9detractor · 95%
- Dietary fat load-1.6no signal · 29%
- Alcohol-1.3no signal · 17%
- Insoluble fibre-0.9no signal · 15%
- Spicy / capsaicin+0.8no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Mucosal barrier integrity ↓60
- DNAFUT2 non-secretor lowers mucosal fucosylation
- MicrobiomeAkkermansia low → thinner mucus layer
- Inflammatory signalling ↑35
- MicrobiomeBacteroides fragilis expansion
- WearableHRV 24 ms, trending down
- Butyrate / short-chain fatty acid production ↓25
- MicrobiomeF. prausnitzii depleted
- Autonomic recovery ↓20
- Wearable2,436 steps/day
DNA
Fictional pharmacogenomic panel
- FUT2 rs601338 AA (non-secretor)Reduced mucosal fucosylation
- CYP2D6 Normal metabolizerExpected exposure
Microbiome
Shannon diversity 2.3 · butyrate capacity 46/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisHigh
- Bifidobacterium longumLow
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 33 ms
- Sleep
- 6.3 h
- Steps
- 3,490
- Resting HR
- 66 bpm
Daily log: GI score 30, nutritional resilience 57, adherence 97.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Keep meals regular; three to four moderate portions spaced through the day
- Include a cooked vegetable portion with each main meal
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Log the daily check-in; one line is enough
- A 15-minute walk after lunch
- Keep the sleep window steady
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- No additional supplements this week
- Fictional demo item: continue vitamin D as before
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.