Patient P-01888
Synthetic patientNBL-101 · Day 116 · 45–54 · M · baseline S14Steering view · 3DOpen companion preview
Therapy response
Improving
Tolerance
Stable
GI state
Unstable
Inflammatory state
Unstable
Nutritional resilience
Unstable
Discontinuation risk
96%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S14
- Day 50 Trajectory diverged from prediction — Observed response fell below the model's expected path.
What changed?
Trajectory began diverging from predicted response on Day 50.
Primary contributors, last 14 days
- Treatment adherence+6
- GI instability-4
- Inflammatory activity-3
- Nutritional resilience-3
What helped?
No interventions yet.
LIFE OS recommendation
GI Support Protocol GI-04
92%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 84% showed improvement
- median effect visible after 8 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
GI burden
Companion70.4/100
stable · -0.8 vs previous 14 d
Toxicity
Blood52.9/100
stable · +0.2 vs previous 14 d
Sleep quality
Wearable16.1/100
worsening · -3.5 vs previous 14 d
Energy level
Daily log1.7/10
improving · +0.3 vs previous 14 d
Stress level
Daily log7.2/10
stable · +0.2 vs previous 14 d
Steps
Wearable6,649
stable · -45 vs previous 14 d
Adherence
Companion45.4 %
stable · -0.9 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards restoration · 33 from the failing basin, 69 from restoration.
Would help
Would not help
- Keep histamine lowGI +4.9 next day on high-intake days · n 24
- Keep simple carbs lowGI +4.3 next day on high-intake days · n 20
- Keep fat lowGI +3.1 next day on high-intake days · n 18
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Histamine load+4.9detractor · 95%
- Simple carbohydrates+4.3detractor · 95%
- Dietary fat load+3.1detractor · 67%
- Spicy / capsaicin-1.9no signal · 38%
- Alcohol-1.6no signal · 30%
- Insoluble fibre+0.5no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Mucosal barrier integrity ↓90
- DNAFUT2 non-secretor lowers mucosal fucosylation
- MicrobiomeAkkermansia low → thinner mucus layer
- Daily logGI symptom score 70 and rising
- WearableSleep 5.1 h, below personal baseline
- Inflammatory signalling ↓45
- MicrobiomeBacteroides fragilis expansion
- BloodInflammatory load index 61
- Butyrate / short-chain fatty acid production ↓45
- MicrobiomeF. prausnitzii depleted
- Daily logFibre intake low in recent food logs
- Autonomic recovery ↑45
- WearableResting HR 85 bpm
- WearableShort sleep window
- Drug metabolism and exposure ↑20
- BloodToxicity index 53
DNA
Fictional pharmacogenomic panel
- FUT2 rs601338 AA (non-secretor)Reduced mucosal fucosylation
- CYP2D6 Normal metabolizerExpected exposure
Microbiome
Shannon diversity 2.5 · butyrate capacity 45/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisHigh
- Bifidobacterium longumLow
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 48 ms
- Sleep
- 5.2 h
- Steps
- 6,416
- Resting HR
- 85 bpm
Daily log: GI score 70, nutritional resilience 35, adherence 45.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- Keep the current walking rhythm
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-01377 | 17% | S11 | AD-05 | no change | 42 |
| P-01689 | 17% | S13 | BR-03 | no change | 50 |
| P-01708 | 29% | S07 | CR-01 | improved | 59 |
| P-01371 | 24% | S06 | CR-01 | improved | 63 |
| P-01388 | 23% | S17 | CR-01 | improved | 59 |
| P-01835 | 23% | S17 | CR-01 | improved | 56 |
| P-01877 | 23% | S01 | CR-01 | improved | 67 |
| P-01696 | 22% | S20 | CR-01 | improved | 59 |
| P-01442 | 20% | S13 | CR-01 | improved | 61 |
| P-01430 | 18% | S05 | CR-01 | improved | 54 |
| P-01396 | 53% | S14 | GI-04 | worsened | 51 |
| P-01572 | 48% | S14 | GI-04 | worsened | 41 |