Patient P-01897
Synthetic patientNBL-101 · Day 111 · 55–64 · M · baseline S14Steering view · 3DOpen companion preview
Therapy response
Improving
Tolerance
Deteriorating
GI state
Unstable
Inflammatory state
Unstable
Nutritional resilience
Unstable
Discontinuation risk
96%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S14
- Day 48 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 57 ME-01 recommended — Monitoring Escalation ME-01
- Day 58 Patient accepted — Started ME-01 in the companion
- Day 61 Deterioration detected before clinical escalation — Monitoring Escalation ME-01
What changed?
Trajectory began diverging from predicted response on Day 48.
Primary contributors, last 14 days
- Treatment adherence+9
- Toxicity+5
- Nutritional resilience-3
What helped?
- Monitoring Escalation ME-01Day 57Result: deterioration detected before clinical escalation
LIFE OS recommendation
GI Support Protocol GI-04
92%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 83% showed improvement
- median effect visible after 8 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
GI burden
Companion73.7/100
worsening · +8.2 vs previous 14 d
Toxicity
Blood51.5/100
stable · +0.1 vs previous 14 d
Sleep quality
Wearable6.5/100
worsening · -5.6 vs previous 14 d
Energy level
Daily log0.9/10
worsening · -0.5 vs previous 14 d
Stress level
Daily log7/10
worsening · +0.4 vs previous 14 d
Steps
Wearable483
worsening · -354 vs previous 14 d
Adherence
Companion44.7 %
stable · -0.1 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards restoration · 22 from the failing basin, 77 from restoration.
Would help
Would not help
- Keep simple carbs lowGI +4.1 next day on high-intake days · n 23
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Simple carbohydrates+4.1detractor · 95%
- Histamine load-1.6no signal · 45%
- Alcohol-1.5no signal · 35%
- Spicy / capsaicin+0.7no signal · 18%
- Dietary fat load+0.2no signal · 15%
- Insoluble fibre+0.1no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Autonomic recovery ↑65
- WearableResting HR 79 bpm
- Wearable483 steps/day
- WearableShort sleep window
- Mucosal barrier integrity ↓60
- MicrobiomeAkkermansia low → thinner mucus layer
- Daily logGI symptom score 74 and rising
- WearableSleep 5.0 h, below personal baseline
- Butyrate / short-chain fatty acid production ↓45
- MicrobiomeF. prausnitzii depleted
- Daily logFibre intake low in recent food logs
- Inflammatory signalling ↓25
- BloodInflammatory load index 62
- Drug metabolism and exposure ↑20
- BloodToxicity index 52
DNA
Fictional pharmacogenomic panel
- CYP2D6 Intermediate metabolizerExpected exposure
Microbiome
Shannon diversity 2 · butyrate capacity 45/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisNormal
- Bifidobacterium longumNormal
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 42 ms
- Sleep
- 4.9 h
- Steps
- 783
- Resting HR
- 81 bpm
Daily log: GI score 74, nutritional resilience 29, adherence 45.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- A 15-minute walk after lunch
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-01463 | 66% | S14 | NP-02 | no change | 41 |
| P-01841 | 64% | S14 | — | — | 48 |
| P-01572 | 61% | S14 | GI-04 | worsened | 41 |
| P-01830 | 58% | S14 | — | — | 44 |
| P-01762 | 57% | S14 | NP-02 | no change | 40 |
| P-01721 | 56% | S14 | — | — | 37 |
| P-01888 | 55% | S14 | — | — | 56 |
| P-01612 | 52% | S14 | ME-01 | improved | 51 |
| P-01582 | 51% | S14 | GI-04 | no change | 45 |
| P-01646 | 51% | S14 | GI-04 | no change | 42 |
| P-01656 | 51% | S14 | ME-01 | improved | 41 |
| P-01736 | 51% | S03 | ME-01 | improved | 46 |