Patient P-01899

Synthetic patientNBL-101 · Day 102 · 55–64 · M · baseline S08Steering view · 3D Open companion preview

Therapy response

Unstable

Tolerance

Deteriorating

GI state

Deteriorating

Inflammatory state

Deteriorating

Nutritional resilience

Declining

Discontinuation risk

20%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 NBL-101 started — Baseline state S08
Day 86 Trajectory diverged from prediction — Observed response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 86.

Primary contributors, last 14 days

Inflammatory activity+11
Nutritional resilience-10
Toxicity+9
GI instability+8

What helped?

No interventions yet.

LIFE OS recommendation

No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

GI burden

Companion

10.1/100

improving · -13.1 vs previous 14 d

Toxicity

Blood

19.5/100

worsening · +2.9 vs previous 14 d

Sleep quality

Wearable

42.3/100

improving · +9.6 vs previous 14 d

Energy level

Daily log

5.4/10

stable · +0.0 vs previous 14 d

Stress level

Daily log

2.8/10

improving · -0.6 vs previous 14 d

Steps

Wearable

7,654

stable · +274 vs previous 14 d

Adherence

Companion

87.2 %

worsening · -7.9 vs previous 14 d

This trajectory is decaying — what would help, what would not

Steering view →

Heading towards failing · 73 from the failing basin, 42 from restoration.

Would help

No untried action with strong evidence. Compose one from primitives.

Would not help

Keep spicy low
GI +2.5 next day on high-intake days · n 14

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Spicy / capsaicin
+2.5detractor · 65%
Simple carbohydrates
-1.9no signal · 39%
Insoluble fibre
+1.8no signal · 35%
Histamine load
-1.4no signal · 38%
Alcohol
+0.9no signal · 20%
Dietary fat load
-0.3no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Inflammatory signalling ↑45
- DNAIL6 -174 variant raises baseline inflammatory tone
- MicrobiomeBacteroides fragilis expansion
Drug metabolism and exposure ↑35
- DNADPYD *2A → slower clearance
Mucosal barrier integrity ↓30
- MicrobiomeAkkermansia low → thinner mucus layer
Autonomic recovery ↑20
- WearableShort sleep window

DNA

Fictional pharmacogenomic panel

IL6 -174 G/C
Higher inflammatory tone
DPYD *2A heterozygous
Slower drug clearance
CYP2D6 Normal metabolizer
Expected exposure

Microbiome

Shannon diversity 3.9 · butyrate capacity 69/100

Akkermansia muciniphilaLow
Faecalibacterium prausnitziiNormal
Bacteroides fragilisHigh
Bifidobacterium longumNormal
EnterobacteriaceaeNormal

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 51 ms
Sleep: 7.1 h
Steps: 8,062
Resting HR: 61 bpm

Daily log: GI score 10, nutritional resilience 71, adherence 87.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Keep fibre steady; no new sources this week
Avoid known triggers for now: fried or oily food, dairy, alcohol

What to do

Log the daily check-in; one line is enough
Keep the current walking rhythm
Protect a 7.5-hour sleep window; screens off 30 minutes before
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the scheduled dose as agreed with your care team
No additional supplements this week
Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-01320	35%	S09	HY-01	improved	38
P-01861	35%	S12	HY-01	improved	47
P-01313	34%	S01	BR-03	improved	32
P-01346	34%	S12	DT-01	improved	52
P-01618	33%	S10	GI-04	improved	39
P-01342	32%	S11	DT-01	improved	48
P-01374	32%	S08	HY-01	improved	49
P-01455	32%	S01	GI-04	improved	61
P-01555	32%	S06	GI-04	improved	56
P-01593	32%	S10	HY-01	improved	56
P-01752	32%	S20	DT-01	improved	50
P-01385	31%	S06	HY-01	improved	50