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Patient P-03046

Synthetic patientONX-7 · Day 141 · 65–74 · F · baseline S20Steering view · 3DOpen companion preview
Therapy response
Declining
Tolerance
Improving
GI state
Improving
Inflammatory state
Improving
Nutritional resilience
Stable
Discontinuation risk
45%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 ONX-7 started — Baseline state S20
  2. Day 98 Trajectory diverged from prediction — Observed response fell below the model's expected path.
  3. Day 102 GI-04 recommended — GI Support Protocol GI-04
  4. Day 103 Patient accepted — Started GI-04 in the companion
  5. Day 111 No meaningful change — GI Support Protocol GI-04

What changed?

Trajectory began diverging from predicted response on Day 98.

Primary contributors, last 14 days
  • GI instability-6
  • Inflammatory activity-6
  • Toxicity-6
  • Nutritional resilience+4
  • Treatment adherence-2

What helped?

  • GI Support Protocol GI-04Day 102
    Result: no meaningful change
LIFE OS recommendation
Dosing / Timing Recommendation DT-01
63%
probability of meaningful tolerance improvement
  • 284 similar trajectories
  • 82% showed improvement
  • median effect visible after 5 days
View similar patientsSimulateAdd to intervention cohortAll evidence

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

Energy level
Daily log
4/10
improving · +0.5 vs previous 14 d
Stress level
Daily log
5.7/10
improving · -0.4 vs previous 14 d
Pessimism score
Daily log
5.2/10
stable · -0.1 vs previous 14 d
Sleep quality
Wearable
30.8/100
improving · +5.8 vs previous 14 d
Libido
Daily log
3/10
improving · +0.2 vs previous 14 d
HRV
Wearable
53.9 ms
improving · +4.7 vs previous 14 d
Toxicity
Blood
39.1/100
improving · -5.2 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →

Heading towards restoration · 42 from the failing basin, 46 from restoration.

Would help
  • DT-01 Dosing / Timing Recommendation
    82% improved among 11 similar · onset 5 d · confidence 62%
  • SC-12 Supportive Compound
    100% improved among 8 similar · onset 6 d · confidence 62%
  • NP-02 Dietary Support Protocol
    57% improved among 14 similar · onset 10 d · confidence 62%
  • More protein
    GI -3.6 next day on high-intake days · n 15
Would not help
  • GI-04 GI Support Protocol
    already tried, no meaningful change
  • AD-05 Adherence Support
    only 33% improved among 12 similar
  • Keep fat low
    GI +3.9 next day on high-intake days · n 19
State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

  • Dietary fat load
    +3.9detractor · 95%
  • Protein
    -3.6supporter · 95%
  • Alcohol
    +1.6no signal · 49%
  • Lactose
    +1no signal · 30%
  • Histamine load
    +0.6no signal · 18%
  • Caffeine
    -0.4no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure
  • Butyrate / short-chain fatty acid production ↓80
    • MicrobiomeButyrate capacity 32/100
    • MicrobiomeF. prausnitzii depleted
    • Daily logFibre intake low in recent food logs
  • Mucosal barrier integrity ↓30
    • Daily logGI symptom score 47 and rising
    • WearableSleep 6.0 h, below personal baseline
  • Inflammatory signalling ↓25
    • BloodInflammatory load index 47
  • Autonomic recovery ↑20
    • WearableShort sleep window
DNA
Fictional pharmacogenomic panel
  • CYP2D6 Normal metabolizer
    Expected exposure
Microbiome
Shannon diversity 3.1 · butyrate capacity 32/100
  • Akkermansia muciniphilaNormal
  • Faecalibacterium prausnitziiLow
  • Bacteroides fragilisNormal
  • Bifidobacterium longumNormal
  • EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
HRV
51 ms
Sleep
5.8 h
Steps
5,470
Resting HR
71 bpm
Daily log: GI score 47, nutritional resilience 46, adherence 68.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview
What to eat
  • Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
  • Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
  • Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
  • Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
  • Track each bowel movement today: time, stool form, urgency, overnight waking
  • A 15-minute walk after lunch
  • Protect a 7.5-hour sleep window; screens off 30 minutes before
  • Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
  • Take the scheduled dose as agreed with your care team
  • Electrolyte solution, one sachet after any loose stool
  • Fictional demo item: oral nutrition supplement with lunch

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Sort by similaritySort by interventionSort by outcomeSort by stateSort by response
PatientSimilarityBaselineInterventionOutcomeResponse today
P-0338243%S01GI-04improved56
P-0338439%S01——55
P-0307430%S01——60
P-0338126%S01——55
P-0338926%S01——50
P-0344326%S01——52
P-0309225%S01——61
P-0325524%S01HY-01improved53
P-0301423%S01——32
P-0317723%S01——28
P-0335748%S02CR-01improved50
P-0309036%S02GI-04improved48