Patient P-03046

Synthetic patientONX-7 · Day 141 · 65–74 · F · baseline S20Steering view · 3D Open companion preview

Therapy response

Declining

Tolerance

Improving

GI state

Improving

Inflammatory state

Improving

Nutritional resilience

Stable

Discontinuation risk

45%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 ONX-7 started — Baseline state S20
Day 98 Trajectory diverged from prediction — Observed response fell below the model's expected path.
Day 102 GI-04 recommended — GI Support Protocol GI-04
Day 103 Patient accepted — Started GI-04 in the companion
Day 111 No meaningful change — GI Support Protocol GI-04

What changed?

Trajectory began diverging from predicted response on Day 98.

Primary contributors, last 14 days

GI instability-6
Inflammatory activity-6
Toxicity-6
Nutritional resilience+4
Treatment adherence-2

What helped?

GI Support Protocol GI-04Day 102
Result: no meaningful change

LIFE OS recommendation

Dosing / Timing Recommendation DT-01

63%

probability of meaningful tolerance improvement

284 similar trajectories
82% showed improvement
median effect visible after 5 days

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

Energy level

Daily log

4/10

improving · +0.5 vs previous 14 d

Stress level

Daily log

5.7/10

improving · -0.4 vs previous 14 d

Pessimism score

Daily log

5.2/10

stable · -0.1 vs previous 14 d

Sleep quality

Wearable

30.8/100

improving · +5.8 vs previous 14 d

Libido

Daily log

3/10

improving · +0.2 vs previous 14 d

HRV

Wearable

53.9 ms

improving · +4.7 vs previous 14 d

Toxicity

Blood

39.1/100

improving · -5.2 vs previous 14 d

This trajectory is decaying — what would help, what would not

Steering view →

Heading towards restoration · 42 from the failing basin, 46 from restoration.

Would help

DT-01 Dosing / Timing Recommendation
82% improved among 11 similar · onset 5 d · confidence 62%
SC-12 Supportive Compound
100% improved among 8 similar · onset 6 d · confidence 62%
NP-02 Dietary Support Protocol
57% improved among 14 similar · onset 10 d · confidence 62%
More protein
GI -3.6 next day on high-intake days · n 15

Would not help

GI-04 GI Support Protocol
already tried, no meaningful change
AD-05 Adherence Support
only 33% improved among 12 similar
Keep fat low
GI +3.9 next day on high-intake days · n 19

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Dietary fat load
+3.9detractor · 95%
Protein
-3.6supporter · 95%
Alcohol
+1.6no signal · 49%
Lactose
+1no signal · 30%
Histamine load
+0.6no signal · 18%
Caffeine
-0.4no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Butyrate / short-chain fatty acid production ↓80
- MicrobiomeButyrate capacity 32/100
- MicrobiomeF. prausnitzii depleted
- Daily logFibre intake low in recent food logs
Mucosal barrier integrity ↓30
- Daily logGI symptom score 47 and rising
- WearableSleep 6.0 h, below personal baseline
Inflammatory signalling ↓25
- BloodInflammatory load index 47
Autonomic recovery ↑20
- WearableShort sleep window

DNA

Fictional pharmacogenomic panel

CYP2D6 Normal metabolizer
Expected exposure

Microbiome

Shannon diversity 3.1 · butyrate capacity 32/100

Akkermansia muciniphilaNormal
Faecalibacterium prausnitziiLow
Bacteroides fragilisNormal
Bifidobacterium longumNormal
EnterobacteriaceaeNormal

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 51 ms
Sleep: 5.8 h
Steps: 5,470
Resting HR: 71 bpm

Daily log: GI score 47, nutritional resilience 46, adherence 68.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
Avoid known triggers for now: fried or oily food, dairy, alcohol

What to do

Track each bowel movement today: time, stool form, urgency, overnight waking
A 15-minute walk after lunch
Protect a 7.5-hour sleep window; screens off 30 minutes before
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the scheduled dose as agreed with your care team
Electrolyte solution, one sachet after any loose stool
Fictional demo item: oral nutrition supplement with lunch

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-03357	48%	S02	CR-01	improved	50
P-03465	47%	S17	CR-01	improved	65
P-03260	46%	S19	—	—	54
P-03267	46%	S05	—	—	62
P-03166	45%	S20	CR-01	improved	62
P-03352	43%	S19	—	—	59
P-03382	43%	S01	GI-04	improved	56
P-03123	41%	S14	GI-04	improved	50
P-03201	41%	S15	GI-04	improved	68
P-03146	39%	S14	GI-04	improved	53
P-03225	39%	S19	GI-04	improved	50
P-03271	39%	S19	—	—	66