Patient P-03102
Therapy response
Unstable
Tolerance
Favorable
GI state
Deteriorating
Inflammatory state
Deteriorating
Nutritional resilience
Declining
Discontinuation risk
40%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 ONX-7 started — Baseline state S19
- Day 15 Trajectory diverged from prediction — Observed response fell below the model's expected path.
What changed?
Trajectory began diverging from predicted response on Day 15.
Primary contributors, last 14 days
- GI instability+16
- Inflammatory activity+12
- Nutritional resilience-5
- Treatment adherence-5
What helped?
No interventions yet.
LIFE OS recommendation
No intervention is indicated right now. The trajectory is stable relative to similar patients.
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Mucosal barrier integrity ↓40
- MicrobiomeAkkermansia low → thinner mucus layer
- WearableSleep 5.8 h, below personal baseline
- Autonomic recovery ↓40
- Wearable2,839 steps/day
- WearableShort sleep window
- Inflammatory signalling ↑35
- MicrobiomeBacteroides fragilis expansion
- WearableHRV 33 ms, trending down
- Butyrate / short-chain fatty acid production ↓35
- MicrobiomeButyrate capacity 34/100
- Drug metabolism and exposure ↑35
- DNADPYD *2A → slower clearance
DNA
Fictional pharmacogenomic panel
- DPYD *2A heterozygousSlower drug clearance
- CYP2D6 Normal metabolizerExpected exposure
Microbiome
Shannon diversity 2.5 · butyrate capacity 34/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiNormal
- Bacteroides fragilisHigh
- Bifidobacterium longumLow
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 41 ms
- Sleep
- 6.8 h
- Steps
- 3,954
- Resting HR
- 63 bpm
Daily log: GI score 33, nutritional resilience 60, adherence 88.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Keep meals regular; three to four moderate portions spaced through the day
- Include a cooked vegetable portion with each main meal
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Log the daily check-in; one line is enough
- A 15-minute walk after lunch
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- No additional supplements this week
- Fictional demo item: continue vitamin D as before
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-03484 | 45% | S07 | DT-01 | improved | 49 |
| P-03233 | 43% | S19 | DT-01 | improved | 47 |
| P-03172 | 42% | S17 | DT-01 | no change | 48 |
| P-03235 | 42% | S13 | GI-04 | improved | 29 |
| P-03277 | 41% | S14 | BR-03 | improved | 41 |
| P-03418 | 41% | S11 | — | — | 38 |
| P-03494 | 41% | S18 | — | — | 38 |
| P-03173 | 40% | S17 | — | — | 39 |
| P-03347 | 40% | S04 | — | — | 32 |
| P-03389 | 40% | S01 | — | — | 50 |
| P-03108 | 39% | S19 | — | — | 32 |
| P-03131 | 39% | S11 | — | — | 30 |