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Patient P-03129

Synthetic patientONX-7 · Day 138 · 75+ · M · baseline S18Steering view · 3DOpen companion preview
Therapy response
Unstable
Tolerance
Improving
GI state
Improving
Inflammatory state
Improving
Nutritional resilience
Improving
Discontinuation risk
9%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 ONX-7 started — Baseline state S18
  2. Day 90 AD-05 recommended — Adherence Support AD-05
  3. Day 91 Patient accepted — Started AD-05 in the companion
  4. Day 96 No meaningful change — Adherence Support AD-05
  5. Day 114 Trajectory diverged from prediction — Observed response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 114.

Primary contributors, last 14 days
  • Toxicity-13
  • GI instability-9
  • Inflammatory activity-9
  • Nutritional resilience+5
  • Treatment adherence-5

What helped?

  • Adherence Support AD-05Day 90
    Result: no meaningful change
LIFE OS recommendation
No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

Energy level
Daily log
6/10
improving · +0.4 vs previous 14 d
Stress level
Daily log
3.6/10
improving · -0.3 vs previous 14 d
Pessimism score
Daily log
5/10
worsening · +0.2 vs previous 14 d
Sleep quality
Wearable
38.1/100
improving · +5.4 vs previous 14 d
Libido
Daily log
5.5/10
improving · +0.4 vs previous 14 d
HRV
Wearable
43.8 ms
improving · +2.2 vs previous 14 d
Toxicity
Blood
8.3/100
stable · +0.1 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →

Heading towards failing · 76 from the failing basin, 47 from restoration.

Would help
  • No untried action with strong evidence. Compose one from primitives.
  • More protein
    GI -5.5 next day on high-intake days · n 20
Would not help
  • AD-05 Adherence Support
    already tried, no meaningful change
  • Keep caffeine low
    GI +5.5 next day on high-intake days · n 23
  • Keep lactose low
    GI +5 next day on high-intake days · n 17
State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

  • Caffeine
    +5.5detractor · 95%
  • Protein
    -5.5supporter · 95%
  • Lactose
    +5detractor · 95%
  • Dietary fat load
    +2.1no signal · 39%
  • Alcohol
    -1.7no signal · 30%
  • Histamine load
    -1no signal · 19%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure
  • Mucosal barrier integrity ↓40
    • MicrobiomeAkkermansia low → thinner mucus layer
    • WearableSleep 5.9 h, below personal baseline
  • Drug metabolism and exposure ↑40
    • DNACYP2D6 poor metabolizer → higher exposure
  • Butyrate / short-chain fatty acid production ↓25
    • MicrobiomeF. prausnitzii depleted
  • Inflammatory signalling ↓20
    • MicrobiomeBacteroides fragilis expansion
  • Autonomic recovery ↑20
    • WearableShort sleep window
DNA
Fictional pharmacogenomic panel
  • CYP2D6 Poor metabolizer
    Higher exposure at standard dose
  • MTHFR C677T
    Reduced folate turnover
Microbiome
Shannon diversity 3.6 · butyrate capacity 65/100
  • Akkermansia muciniphilaLow
  • Faecalibacterium prausnitziiLow
  • Bacteroides fragilisHigh
  • Bifidobacterium longumNormal
  • EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
HRV
44 ms
Sleep
6.3 h
Steps
4,993
Resting HR
67 bpm
Daily log: GI score 11, nutritional resilience 71, adherence 83.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview
What to eat
  • Keep meals regular; three to four moderate portions spaced through the day
  • Include a cooked vegetable portion with each main meal
  • Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
  • Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
  • Log the daily check-in; one line is enough
  • A 15-minute walk after lunch
  • Protect a 7.5-hour sleep window; screens off 30 minutes before
  • Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
  • Take the scheduled dose as agreed with your care team
  • No additional supplements this week
  • Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Sort by similaritySort by interventionSort by outcomeSort by stateSort by response
PatientSimilarityBaselineInterventionOutcomeResponse today
P-0338055%S16AD-05improved34
P-0342443%S12AD-05improved41
P-0337341%S17BR-03improved34
P-0327740%S14BR-03improved41
P-0330839%S04BR-03improved39
P-0344138%S19AD-05improved37
P-0321537%S16HY-01improved44
P-0323537%S13GI-04improved29
P-0320436%S16AD-05improved48
P-0331736%S08HY-01improved45
P-0342636%S18BR-03improved27
P-0323335%S19DT-01improved47