Patient P-03166
Therapy response
Improving
Tolerance
Improving
GI state
Improving
Inflammatory state
Improving
Nutritional resilience
Unstable
Discontinuation risk
47%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 ONX-7 started — Baseline state S20
- Day 97 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 102 CR-01 recommended — Clinician Review CR-01
- Day 103 Patient accepted — Started CR-01 in the companion
- Day 108 Deterioration detected before clinical escalation — Clinician Review CR-01
What changed?
Trajectory began diverging from predicted response on Day 97.
Primary contributors, last 14 days
- Toxicity-13
- GI instability-9
- Inflammatory activity-9
- Nutritional resilience+6
What helped?
- Clinician Review CR-01Day 102Result: deterioration detected before clinical escalation
LIFE OS recommendation
GI Support Protocol GI-04
59%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 82% showed improvement
- median effect visible after 8 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
Energy level
Daily log2.9/10
worsening · -0.3 vs previous 14 d
Stress level
Daily log6.4/10
stable · +0.2 vs previous 14 d
Pessimism score
Daily log4.7/10
stable · +0.1 vs previous 14 d
Sleep quality
Wearable29.4/100
improving · +3.9 vs previous 14 d
Libido
Daily log3.4/10
stable · -0.0 vs previous 14 d
HRV
Wearable33 ms
stable · -0.8 vs previous 14 d
Toxicity
Blood37.6/100
stable · +0.9 vs previous 14 d
This trajectory is doing well — what to keep, what to watch
Steering view →Heading towards restoration · 45 from the failing basin, 48 from restoration.
Good elements to keep
- Clinician Review CR-01intervention · steering +16.7
- Protein (supports)perturbation · steering +7.2
- Proteinsupporter · GI -4.5 next day
Main detractors to watch
- Low butyrate capacityhidden · steering -17.5
- Low microbial diversityhidden · steering -7.7
- Enterobacteriaceae elevatedhidden · steering -7.4
- Dietary fat loadperturbation · steering -7.4
- Dietary fat loaddetractor · GI +4.1 next day
- Lactosedetractor · GI +2.7 next day
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Protein-4.5supporter · 95%
- Dietary fat load+4.1detractor · 95%
- Lactose+2.7detractor · 72%
- Histamine load-0.8no signal · 22%
- Alcohol-0.5no signal · 17%
- Caffeine+0.3no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Butyrate / short-chain fatty acid production ↓55
- MicrobiomeButyrate capacity 44/100
- Daily logFibre intake low in recent food logs
- Autonomic recovery ↑45
- WearableResting HR 75 bpm
- WearableShort sleep window
- Inflammatory signalling ↓40
- BloodInflammatory load index 49
- WearableHRV 33 ms, trending down
- Mucosal barrier integrity ↓20
- Daily logGI symptom score 54 and rising
DNA
Fictional pharmacogenomic panel
- CYP2D6 Normal metabolizerExpected exposure
Microbiome
Shannon diversity 1.8 · butyrate capacity 44/100
- Akkermansia muciniphilaNormal
- Faecalibacterium prausnitziiNormal
- Bacteroides fragilisNormal
- Bifidobacterium longumNormal
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 32 ms
- Sleep
- 6.3 h
- Steps
- 4,345
- Resting HR
- 77 bpm
Daily log: GI score 54, nutritional resilience 42, adherence 72.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- Keep the current walking rhythm
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.