Patient P-03166
Therapy response
Improving
Tolerance
Improving
GI state
Improving
Inflammatory state
Improving
Nutritional resilience
Unstable
Discontinuation risk
47%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 ONX-7 started — Baseline state S20
- Day 97 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 102 CR-01 recommended — Clinician Review CR-01
- Day 103 Patient accepted — Started CR-01 in the companion
- Day 108 Deterioration detected before clinical escalation — Clinician Review CR-01
What changed?
Trajectory began diverging from predicted response on Day 97.
Primary contributors, last 14 days
- Toxicity-13
- GI instability-9
- Inflammatory activity-9
- Nutritional resilience+6
What helped?
- Clinician Review CR-01Day 102Result: deterioration detected before clinical escalation
LIFE OS recommendation
GI Support Protocol GI-04
59%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 82% showed improvement
- median effect visible after 8 days
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Butyrate / short-chain fatty acid production ↓55
- MicrobiomeButyrate capacity 44/100
- Daily logFibre intake low in recent food logs
- Autonomic recovery ↑45
- WearableResting HR 75 bpm
- WearableShort sleep window
- Inflammatory signalling ↓40
- BloodInflammatory load index 49
- WearableHRV 33 ms, trending down
- Mucosal barrier integrity ↓20
- Daily logGI symptom score 54 and rising
DNA
Fictional pharmacogenomic panel
- CYP2D6 Normal metabolizerExpected exposure
Microbiome
Shannon diversity 1.8 · butyrate capacity 44/100
- Akkermansia muciniphilaNormal
- Faecalibacterium prausnitziiNormal
- Bacteroides fragilisNormal
- Bifidobacterium longumNormal
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 32 ms
- Sleep
- 6.3 h
- Steps
- 4,345
- Resting HR
- 77 bpm
Daily log: GI score 54, nutritional resilience 42, adherence 72.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- Keep the current walking rhythm
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-03382 | 45% | S01 | GI-04 | improved | 56 |
| P-03201 | 44% | S15 | GI-04 | improved | 68 |
| P-03099 | 43% | S17 | CR-01 | improved | 55 |
| P-03225 | 43% | S19 | GI-04 | improved | 50 |
| P-03465 | 42% | S17 | CR-01 | improved | 65 |
| P-03191 | 41% | S19 | GI-04 | improved | 51 |
| P-03031 | 37% | S16 | CR-01 | improved | 49 |
| P-03090 | 37% | S02 | GI-04 | improved | 48 |
| P-03146 | 37% | S14 | GI-04 | improved | 53 |
| P-03070 | 36% | S14 | GI-04 | improved | 51 |
| P-03123 | 36% | S14 | GI-04 | improved | 50 |
| P-03357 | 36% | S02 | CR-01 | improved | 50 |