Patient P-03235

Synthetic patientONX-7 · Day 148 · 65–74 · M · baseline S13Steering view · 3D Open companion preview

Therapy response

Unstable

Tolerance

Favorable

GI state

Deteriorating

Inflammatory state

Deteriorating

Nutritional resilience

Favorable

Discontinuation risk

35%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 ONX-7 started — Baseline state S13
Day 29 Trajectory diverged from prediction — Observed response fell below the model's expected path.
Day 30 GI-04 recommended — GI Support Protocol GI-04
Day 31 Patient accepted — Started GI-04 in the companion
Day 39 GI symptom burden −12% vs expected — GI Support Protocol GI-04
Day 45 Tolerance state changed — Unstable → Improving

What changed?

Trajectory began diverging from predicted response on Day 29.

Primary contributors, last 14 days

GI instability+16
Inflammatory activity+11
Treatment adherence+5
Nutritional resilience-3
Toxicity-3

What helped?

GI Support Protocol GI-04Day 30
Result: symptom burden −12%

LIFE OS recommendation

No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

Energy level

Daily log

5.3/10

worsening · -0.2 vs previous 14 d

Stress level

Daily log

3.6/10

stable · +0.1 vs previous 14 d

Pessimism score

Daily log

4.3/10

stable · +0.2 vs previous 14 d

Sleep quality

Wearable

33.8/100

improving · +4.2 vs previous 14 d

Libido

Daily log

5.3/10

stable · 0.0 vs previous 14 d

HRV

Wearable

45.1 ms

stable · +1.4 vs previous 14 d

Toxicity

Blood

13.3/100

worsening · +1.6 vs previous 14 d

This trajectory is decaying — what would help, what would not

Steering view →

Heading towards failing · 62 from the failing basin, 49 from restoration.

Would help

No untried action with strong evidence. Compose one from primitives.
More protein
GI -4.1 next day on high-intake days · n 19

Would not help

AD-05 Adherence Support
only 29% improved among 14 similar
Keep lactose low
GI +3.6 next day on high-intake days · n 17

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Protein
-4.1supporter · 95%
Lactose
+3.6detractor · 95%
Histamine load
-1.4no signal · 38%
Alcohol
-1.4no signal · 38%
Caffeine
-1.1no signal · 27%
Dietary fat load
0no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Mucosal barrier integrity ↓40
- MicrobiomeAkkermansia low → thinner mucus layer
- WearableSleep 6.0 h, below personal baseline
Inflammatory signalling ↑20
- MicrobiomeBacteroides fragilis expansion
Autonomic recovery ↓20
- WearableShort sleep window

DNA

Fictional pharmacogenomic panel

CYP2D6 Intermediate metabolizer
Expected exposure

Microbiome

Shannon diversity 4.2 · butyrate capacity 51/100

Akkermansia muciniphilaLow
Faecalibacterium prausnitziiNormal
Bacteroides fragilisHigh
Bifidobacterium longumNormal
EnterobacteriaceaeHigh

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 47 ms
Sleep: 6.0 h
Steps: 8,993
Resting HR: 62 bpm

Daily log: GI score 23, nutritional resilience 66, adherence 88.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Keep fibre steady; no new sources this week
Avoid known triggers for now: fried or oily food, dairy, alcohol

What to do

Log the daily check-in; one line is enough
Keep the current walking rhythm
Protect a 7.5-hour sleep window; screens off 30 minutes before
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the scheduled dose as agreed with your care team
No additional supplements this week
Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-03307	40%	S03	ME-01	improved	17
P-03380	40%	S16	AD-05	improved	34
P-03013	39%	S07	GI-04	improved	30
P-03277	39%	S14	BR-03	improved	41
P-03373	39%	S17	BR-03	improved	34
P-03426	39%	S18	BR-03	improved	27
P-03424	38%	S12	AD-05	improved	41
P-03233	37%	S19	DT-01	improved	47
P-03204	35%	S16	AD-05	improved	48
P-03215	35%	S16	HY-01	improved	44
P-03143	33%	S11	DT-01	improved	49
P-03442	33%	S11	DT-01	improved	51