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Patient P-03246

Synthetic patientONX-7 · Day 99 · 55–64 · F · baseline S15Steering view · 3DOpen companion preview
Therapy response
Favorable
Tolerance
Deteriorating
GI state
Deteriorating
Inflammatory state
Deteriorating
Nutritional resilience
Declining
Discontinuation risk
41%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 ONX-7 started — Baseline state S15

What changed?

Trajectory is tracking the baseline prediction.

Primary contributors, last 14 days
  • GI instability+19
  • Inflammatory activity+14
  • Nutritional resilience-12
  • Treatment adherence-5
  • Toxicity+5

What helped?

No interventions yet.

    LIFE OS recommendation
    No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

    Daily trackers

    Molecule settings

    The trackers this program marks as important, last 14 days vs the 14 before.

    Energy level
    Daily log
    5.2/10
    worsening · -0.5 vs previous 14 d
    Stress level
    Daily log
    4.1/10
    worsening · +0.7 vs previous 14 d
    Pessimism score
    Daily log
    3.5/10
    worsening · +0.4 vs previous 14 d
    Sleep quality
    Wearable
    37/100
    worsening · -11.8 vs previous 14 d
    Libido
    Daily log
    4.6/10
    worsening · -0.6 vs previous 14 d
    HRV
    Wearable
    37.3 ms
    worsening · -3.5 vs previous 14 d
    Toxicity
    Blood
    19.3/100
    worsening · +0.7 vs previous 14 d
    This trajectory is decaying — what would help, what would not
    Steering view →

    Heading towards failing · 67 from the failing basin, 21 from restoration.

    Would help
    • No untried action with strong evidence. Compose one from primitives.
    • More protein
      GI -7.2 next day on high-intake days · n 18
    Would not help
    • AD-05 Adherence Support
      only 30% improved among 10 similar
    • Keep lactose low
      GI +6.3 next day on high-intake days · n 22
    • Keep histamine low
      GI +4.9 next day on high-intake days · n 24
    • Keep fat low
      GI +3.8 next day on high-intake days · n 15
    State influencers · digestive

    Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

    • Protein
      -7.2supporter · 95%
    • Lactose
      +6.3detractor · 95%
    • Histamine load
      +4.9detractor · 95%
    • Dietary fat load
      +3.8detractor · 82%
    • Caffeine
      +0.2no signal · 15%
    • Alcohol
      +0.2no signal · 15%

    Biological layers

    Which pathways look influenced, and by which layer of this person's biology.

    Pathways under pressure
    • Mucosal barrier integrity ↓70
      • DNAFUT2 non-secretor lowers mucosal fucosylation
      • MicrobiomeAkkermansia low → thinner mucus layer
      • WearableSleep 6.0 h, below personal baseline
    • Inflammatory signalling ↑60
      • DNAIL6 -174 variant raises baseline inflammatory tone
      • MicrobiomeBacteroides fragilis expansion
      • WearableHRV 37 ms, trending down
    • Butyrate / short-chain fatty acid production ↓60
      • MicrobiomeButyrate capacity 24/100
      • MicrobiomeF. prausnitzii depleted
    • Autonomic recovery ↓45
      • WearableResting HR 73 bpm
      • WearableShort sleep window
    DNA
    Fictional pharmacogenomic panel
    • FUT2 rs601338 AA (non-secretor)
      Reduced mucosal fucosylation
    • IL6 -174 G/C
      Higher inflammatory tone
    • CYP2D6 Intermediate metabolizer
      Expected exposure
    Microbiome
    Shannon diversity 2.4 · butyrate capacity 24/100
    • Akkermansia muciniphilaLow
    • Faecalibacterium prausnitziiLow
    • Bacteroides fragilisHigh
    • Bifidobacterium longumLow
    • EnterobacteriaceaeNormal
    Wearable, last 14 days
    daily evolution fed into the runtime
    HRV
    39 ms
    Sleep
    5.7 h
    Steps
    5,298
    Resting HR
    73 bpm
    Daily log: GI score 26, nutritional resilience 59, adherence 90.

    What this patient sees in NostraAI

    The content that steers the trajectory: what to eat, what to do, what to take.

    Open companion preview
    What to eat
    • Keep meals regular; three to four moderate portions spaced through the day
    • Include a cooked vegetable portion with each main meal
    • Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
    • Avoid known triggers for now: fried or oily food, dairy, alcohol
    What to do
    • Log the daily check-in; one line is enough
    • Keep the current walking rhythm
    • Protect a 7.5-hour sleep window; screens off 30 minutes before
    • Keep hydration steady: small amounts through the day rather than large volumes at once
    What to take
    • Take the scheduled dose as agreed with your care team
    • No additional supplements this week
    • Fictional demo item: continue vitamin D as before

    284 biologically similar trajectories

    Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

    Sort by similaritySort by interventionSort by outcomeSort by stateSort by response
    PatientSimilarityBaselineInterventionOutcomeResponse today
    P-0302750%S20——62
    P-0306447%S10——50
    P-0310745%S17——62
    P-0319645%S05——60
    P-0321445%S18——68
    P-0325445%S06——66
    P-0325845%S14NP-02no change59
    P-0342845%S16——62
    P-0310144%S15——65
    P-0317144%S10——55
    P-0319244%S11——58
    P-0330144%S02——62