Patient P-03246
Therapy response
Favorable
Tolerance
Deteriorating
GI state
Deteriorating
Inflammatory state
Deteriorating
Nutritional resilience
Declining
Discontinuation risk
41%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 ONX-7 started — Baseline state S15
What changed?
Trajectory is tracking the baseline prediction.
Primary contributors, last 14 days
- GI instability+19
- Inflammatory activity+14
- Nutritional resilience-12
- Treatment adherence-5
- Toxicity+5
What helped?
No interventions yet.
LIFE OS recommendation
No intervention is indicated right now. The trajectory is stable relative to similar patients.
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Mucosal barrier integrity ↓70
- DNAFUT2 non-secretor lowers mucosal fucosylation
- MicrobiomeAkkermansia low → thinner mucus layer
- WearableSleep 6.0 h, below personal baseline
- Inflammatory signalling ↑60
- DNAIL6 -174 variant raises baseline inflammatory tone
- MicrobiomeBacteroides fragilis expansion
- WearableHRV 37 ms, trending down
- Butyrate / short-chain fatty acid production ↓60
- MicrobiomeButyrate capacity 24/100
- MicrobiomeF. prausnitzii depleted
- Autonomic recovery ↓45
- WearableResting HR 73 bpm
- WearableShort sleep window
DNA
Fictional pharmacogenomic panel
- FUT2 rs601338 AA (non-secretor)Reduced mucosal fucosylation
- IL6 -174 G/CHigher inflammatory tone
- CYP2D6 Intermediate metabolizerExpected exposure
Microbiome
Shannon diversity 2.4 · butyrate capacity 24/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisHigh
- Bifidobacterium longumLow
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 39 ms
- Sleep
- 5.7 h
- Steps
- 5,298
- Resting HR
- 73 bpm
Daily log: GI score 26, nutritional resilience 59, adherence 90.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Keep meals regular; three to four moderate portions spaced through the day
- Include a cooked vegetable portion with each main meal
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Log the daily check-in; one line is enough
- Keep the current walking rhythm
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- No additional supplements this week
- Fictional demo item: continue vitamin D as before
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-03105 | 43% | S12 | AD-05 | no change | 60 |
| P-03482 | 42% | S05 | AD-05 | no change | 67 |
| P-03204 | 38% | S16 | AD-05 | improved | 48 |
| P-03111 | 35% | S07 | AD-05 | no change | 48 |
| P-03187 | 35% | S12 | AD-05 | no change | 80 |
| P-03424 | 35% | S12 | AD-05 | improved | 41 |
| P-03351 | 32% | S07 | AD-05 | no change | 51 |
| P-03380 | 31% | S16 | AD-05 | improved | 34 |
| P-03129 | 30% | S18 | AD-05 | no change | 32 |
| P-03369 | 30% | S18 | AD-05 | no change | 37 |
| P-03208 | 36% | S02 | BR-03 | improved | 57 |
| P-03277 | 35% | S14 | BR-03 | improved | 41 |