Patient P-03277
Therapy response
Unstable
Tolerance
Favorable
GI state
Deteriorating
Inflammatory state
Deteriorating
Nutritional resilience
Declining
Discontinuation risk
54%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 ONX-7 started — Baseline state S14
- Day 90 BR-03 recommended — Behavioural Recommendation BR-03
- Day 91 Patient accepted — Started BR-03 in the companion
- Day 98 GI symptom burden −12% vs expected — Behavioural Recommendation BR-03
- Day 104 Tolerance state changed — Unstable → Improving
- Day 109 Trajectory diverged from prediction — Observed response fell below the model's expected path.
What changed?
Trajectory began diverging from predicted response on Day 109.
Primary contributors, last 14 days
- GI instability+22
- Nutritional resilience-14
- Inflammatory activity+13
- Treatment adherence+12
What helped?
- Behavioural Recommendation BR-03Day 90Result: symptom burden −12%
LIFE OS recommendation
Monitoring Escalation ME-01
79%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 100% showed improvement
- median effect visible after 3 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
Energy level
Daily log5.5/10
stable · -0.0 vs previous 14 d
Stress level
Daily log3.7/10
worsening · +0.2 vs previous 14 d
Pessimism score
Daily log4.6/10
worsening · +0.3 vs previous 14 d
Sleep quality
Wearable32.2/100
stable · +0.2 vs previous 14 d
Libido
Daily log5.6/10
stable · -0.1 vs previous 14 d
HRV
Wearable45.4 ms
stable · -1.4 vs previous 14 d
Toxicity
Blood10.3/100
worsening · +2.6 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards failing · 59 from the failing basin, 39 from restoration.
Would help
- No untried action with strong evidence. Compose one from primitives.
- More proteinGI -5.6 next day on high-intake days · n 17
Would not help
- AD-05 Adherence Supportonly 29% improved among 14 similar
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Protein-5.6supporter · 95%
- Alcohol+2.3no signal · 49%
- Dietary fat load-0.9no signal · 16%
- Caffeine-0.6no signal · 15%
- Lactose-0.2no signal · 15%
- Histamine load-0.1no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Autonomic recovery ↓40
- Wearable3,938 steps/day
- WearableShort sleep window
- Inflammatory signalling ↑25
- DNAIL6 -174 variant raises baseline inflammatory tone
DNA
Fictional pharmacogenomic panel
- IL6 -174 G/CHigher inflammatory tone
- CYP2D6 Normal metabolizerExpected exposure
- MTHFR C677TReduced folate turnover
Microbiome
Shannon diversity 3.2 · butyrate capacity 73/100
- Akkermansia muciniphilaNormal
- Faecalibacterium prausnitziiNormal
- Bacteroides fragilisNormal
- Bifidobacterium longumNormal
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 46 ms
- Sleep
- 6.4 h
- Steps
- 4,344
- Resting HR
- 59 bpm
Daily log: GI score 31, nutritional resilience 60, adherence 91.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Keep meals regular; three to four moderate portions spaced through the day
- Include a cooked vegetable portion with each main meal
- Keep fibre steady; no new sources this week
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Log the daily check-in; one line is enough
- A 15-minute walk after lunch
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- No additional supplements this week
- Fictional demo item: continue vitamin D as before
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.