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Patient P-03316

Synthetic patientONX-7 · Day 124 · 35–44 · M · baseline S20Steering view · 3DOpen companion preview
Therapy response
Unstable
Tolerance
Improving
GI state
Improving
Inflammatory state
Improving
Nutritional resilience
Improving
Discontinuation risk
15%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 ONX-7 started — Baseline state S20
  2. Day 20 Trajectory diverged from prediction — Observed response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 20.

Primary contributors, last 14 days
  • Treatment adherence+11
  • Toxicity-9
  • Inflammatory activity-6
  • GI instability-5
  • Nutritional resilience+5

What helped?

No interventions yet.

    LIFE OS recommendation
    No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

    Daily trackers

    Molecule settings

    The trackers this program marks as important, last 14 days vs the 14 before.

    Energy level
    Daily log
    5.7/10
    improving · +0.3 vs previous 14 d
    Stress level
    Daily log
    3.3/10
    worsening · +0.2 vs previous 14 d
    Pessimism score
    Daily log
    3.7/10
    stable · -0.1 vs previous 14 d
    Sleep quality
    Wearable
    46.5/100
    improving · +4.1 vs previous 14 d
    Libido
    Daily log
    5.6/10
    improving · +0.2 vs previous 14 d
    HRV
    Wearable
    56.5 ms
    improving · +2.4 vs previous 14 d
    Toxicity
    Blood
    13.1/100
    improving · -6.0 vs previous 14 d
    This trajectory is doing well — what to keep, what to watch
    Steering view →

    Heading towards restoration · 62 from the failing basin, 42 from restoration.

    Good elements to keep
    • Protein (supports)
      perturbation · steering +11.9
    • Butyrate producers intact
      hidden · steering +7.5
    • Daily walks resumed
      perturbation · steering +3.3
    • Protein
      supporter · GI -7.1 next day
    Main detractors to watch
    • Histamine load
      perturbation · steering -11.3
    • FUT2 non-secretor
      hidden · steering -10.6
    • Lactose
      perturbation · steering -9
    • Bacteroides fragilis elevated
      hidden · steering -7.4
    • Histamine load
      detractor · GI +5.3 next day
    • Lactose
      detractor · GI +5.2 next day
    State influencers · digestive

    Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

    • Protein
      -7.1supporter · 95%
    • Histamine load
      +5.3detractor · 95%
    • Lactose
      +5.2detractor · 95%
    • Alcohol
      +1.3no signal · 25%
    • Dietary fat load
      -0.9no signal · 15%
    • Caffeine
      +0.6no signal · 15%

    Biological layers

    Which pathways look influenced, and by which layer of this person's biology.

    Pathways under pressure
    • Autonomic recovery ↑45
      • WearableResting HR 75 bpm
      • WearableShort sleep window
    • Mucosal barrier integrity ↓40
      • DNAFUT2 non-secretor lowers mucosal fucosylation
      • WearableSleep 6.1 h, below personal baseline
    • Butyrate / short-chain fatty acid production ↓25
      • MicrobiomeF. prausnitzii depleted
    • Inflammatory signalling ↓20
      • MicrobiomeBacteroides fragilis expansion
    DNA
    Fictional pharmacogenomic panel
    • FUT2 rs601338 AA (non-secretor)
      Reduced mucosal fucosylation
    • CYP2D6 Normal metabolizer
      Expected exposure
    • MTHFR C677T
      Reduced folate turnover
    Microbiome
    Shannon diversity 3.4 · butyrate capacity 77/100
    • Akkermansia muciniphilaNormal
    • Faecalibacterium prausnitziiLow
    • Bacteroides fragilisHigh
    • Bifidobacterium longumLow
    • EnterobacteriaceaeNormal
    Wearable, last 14 days
    daily evolution fed into the runtime
    HRV
    55 ms
    Sleep
    6.5 h
    Steps
    7,197
    Resting HR
    76 bpm
    Daily log: GI score 25, nutritional resilience 65, adherence 92.

    What this patient sees in NostraAI

    The content that steers the trajectory: what to eat, what to do, what to take.

    Open companion preview
    What to eat
    • Keep meals regular; three to four moderate portions spaced through the day
    • Include a cooked vegetable portion with each main meal
    • Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
    • Avoid known triggers for now: fried or oily food, dairy, alcohol
    What to do
    • Log the daily check-in; one line is enough
    • Keep the current walking rhythm
    • Protect a 7.5-hour sleep window; screens off 30 minutes before
    • Keep hydration steady: small amounts through the day rather than large volumes at once
    What to take
    • Take the scheduled dose as agreed with your care team
    • No additional supplements this week
    • Fictional demo item: continue vitamin D as before

    284 biologically similar trajectories

    Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

    Sort by similaritySort by interventionSort by outcomeSort by stateSort by response
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    P-0327736%S14BR-03improved41
    P-0337336%S17BR-03improved34
    P-0342636%S18BR-03improved27
    P-0342434%S12AD-05improved41
    P-0320433%S16AD-05improved48
    P-0321533%S16HY-01improved44
    P-0323333%S19DT-01improved47
    P-0330733%S03ME-01improved17
    P-0338033%S16AD-05improved34
    P-0340833%S09HY-01improved53