Patient P-03332
Therapy response
Declining
Tolerance
Stable
GI state
Unstable
Inflammatory state
Unstable
Nutritional resilience
Unstable
Discontinuation risk
96%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 ONX-7 started — Baseline state S14
- Day 39 NP-02 recommended — Dietary Support Protocol NP-02
- Day 40 Patient accepted — Started NP-02 in the companion
- Day 50 No meaningful change — Dietary Support Protocol NP-02
- Day 60 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 76 ME-01 recommended — Monitoring Escalation ME-01
- Day 77 Patient accepted — Started ME-01 in the companion
- Day 80 Deterioration detected before clinical escalation — Monitoring Escalation ME-01
What changed?
Trajectory began diverging from predicted response on Day 60.
Primary contributors, last 14 days
- Treatment adherence-23
- GI instability+10
- Inflammatory activity+9
- Nutritional resilience-8
- Toxicity-2
What helped?
- Dietary Support Protocol NP-02Day 39Result: no meaningful change
- Monitoring Escalation ME-01Day 76Result: deterioration detected before clinical escalation
LIFE OS recommendation
GI Support Protocol GI-04
91%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 81% showed improvement
- median effect visible after 8 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
Energy level
Daily log1.6/10
worsening · -1.1 vs previous 14 d
Stress level
Daily log7.7/10
worsening · +0.5 vs previous 14 d
Pessimism score
Daily log5.9/10
worsening · +0.6 vs previous 14 d
Sleep quality
Wearable24.8/100
worsening · -8.3 vs previous 14 d
Libido
Daily log2/10
worsening · -0.2 vs previous 14 d
HRV
Wearable24.9 ms
worsening · -3.6 vs previous 14 d
Toxicity
Blood52.3/100
stable · +0.4 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards failing · 32 from the failing basin, 82 from restoration.
Would help
Would not help
- NP-02 Dietary Support Protocolalready tried, no meaningful change
- AD-05 Adherence Supportonly 13% improved among 8 similar
- Keep fat lowGI +5.7 next day on high-intake days · n 26
- Keep histamine lowGI +5.7 next day on high-intake days · n 23
- Keep lactose lowGI +5.4 next day on high-intake days · n 23
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Protein-6supporter · 95%
- Dietary fat load+5.7detractor · 95%
- Histamine load+5.7detractor · 95%
- Lactose+5.4detractor · 95%
- Caffeine+2.5no signal · 47%
- Alcohol+2.3detractor · 55%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Mucosal barrier integrity ↓90
- DNAFUT2 non-secretor lowers mucosal fucosylation
- MicrobiomeAkkermansia low → thinner mucus layer
- Daily logGI symptom score 77 and rising
- WearableSleep 6.1 h, below personal baseline
- Butyrate / short-chain fatty acid production ↓80
- MicrobiomeButyrate capacity 38/100
- MicrobiomeF. prausnitzii depleted
- Daily logFibre intake low in recent food logs
- Inflammatory signalling ↑65
- DNAIL6 -174 variant raises baseline inflammatory tone
- BloodInflammatory load index 72
- WearableHRV 25 ms, trending down
- Autonomic recovery ↓65
- WearableResting HR 86 bpm
- Wearable3,988 steps/day
- WearableShort sleep window
- Drug metabolism and exposure ↑20
- BloodToxicity index 52
DNA
Fictional pharmacogenomic panel
- FUT2 rs601338 AA (non-secretor)Reduced mucosal fucosylation
- IL6 -174 G/CHigher inflammatory tone
- CYP2D6 Intermediate metabolizerExpected exposure
Microbiome
Shannon diversity 3 · butyrate capacity 38/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisNormal
- Bifidobacterium longumLow
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 27 ms
- Sleep
- 6.0 h
- Steps
- 3,268
- Resting HR
- 87 bpm
Daily log: GI score 77, nutritional resilience 24, adherence 47.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- A 15-minute walk after lunch
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-03105 | 18% | S12 | AD-05 | no change | 60 |
| P-03204 | 18% | S16 | AD-05 | improved | 48 |
| P-03351 | 18% | S07 | AD-05 | no change | 51 |
| P-03482 | 18% | S05 | AD-05 | no change | 67 |
| P-03111 | 17% | S07 | AD-05 | no change | 48 |
| P-03187 | 17% | S12 | AD-05 | no change | 80 |
| P-03034 | 16% | S14 | AD-05 | no change | 30 |
| P-03158 | 16% | S17 | AD-05 | no change | 37 |
| P-03208 | 16% | S02 | BR-03 | improved | 57 |
| P-03099 | 33% | S17 | CR-01 | improved | 55 |
| P-03357 | 28% | S02 | CR-01 | improved | 50 |
| P-03031 | 27% | S16 | CR-01 | improved | 49 |