Patient P-03342
Therapy response
Improving
Tolerance
Deteriorating
GI state
Deteriorating
Inflammatory state
Favorable
Nutritional resilience
Declining
Discontinuation risk
34%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 ONX-7 started — Baseline state S11
- Day 16 Trajectory diverged from prediction — Observed response fell below the model's expected path.
What changed?
Trajectory began diverging from predicted response on Day 16.
Primary contributors, last 14 days
- GI instability+15
- Nutritional resilience-9
- Toxicity+5
- Treatment adherence+3
What helped?
No interventions yet.
LIFE OS recommendation
No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
Energy level
Daily log6.3/10
worsening · -0.3 vs previous 14 d
Stress level
Daily log4.2/10
worsening · +0.3 vs previous 14 d
Pessimism score
Daily log2.3/10
stable · -0.1 vs previous 14 d
Sleep quality
Wearable42.1/100
stable · -1.7 vs previous 14 d
Libido
Daily log5.4/10
stable · +0.0 vs previous 14 d
HRV
Wearable29.5 ms
stable · -0.1 vs previous 14 d
Toxicity
Blood17.2/100
stable · +0.3 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards restoration · 90 from the failing basin, 14 from restoration.
Would help
- No untried action with strong evidence. Compose one from primitives.
- More proteinGI -7.4 next day on high-intake days · n 22
Would not help
- Nothing clearly counter-productive in the record.
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Protein-7.4supporter · 95%
- Lactose+1.9no signal · 26%
- Dietary fat load+1.7no signal · 29%
- Caffeine+0.1no signal · 15%
- Alcohol-0.1no signal · 15%
- Histamine load0no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Drug metabolism and exposure ↑35
- DNADPYD *2A → slower clearance
- Butyrate / short-chain fatty acid production ↓25
- MicrobiomeF. prausnitzii depleted
- Autonomic recovery ↓25
- WearableResting HR 79 bpm
- Inflammatory signalling ↓15
- WearableHRV 30 ms, trending down
DNA
Fictional pharmacogenomic panel
- DPYD *2A heterozygousSlower drug clearance
- CYP2D6 Normal metabolizerExpected exposure
Microbiome
Shannon diversity 3 · butyrate capacity 74/100
- Akkermansia muciniphilaNormal
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisNormal
- Bifidobacterium longumNormal
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 34 ms
- Sleep
- 6.8 h
- Steps
- 7,333
- Resting HR
- 75 bpm
Daily log: GI score 26, nutritional resilience 63, adherence 95.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Keep meals regular; three to four moderate portions spaced through the day
- Include a cooked vegetable portion with each main meal
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Log the daily check-in; one line is enough
- Keep the current walking rhythm
- Keep the sleep window steady
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- No additional supplements this week
- Fictional demo item: continue vitamin D as before
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.