Patient P-03404

Synthetic patientONX-7 · Day 145 · 25–34 · M · baseline S02Steering view · 3D Open companion preview

Therapy response

Unstable

Tolerance

Improving

GI state

Improving

Inflammatory state

Improving

Nutritional resilience

Improving

Discontinuation risk

11%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 ONX-7 started — Baseline state S02
Day 25 Trajectory diverged from prediction — Observed response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 25.

Primary contributors, last 14 days

GI instability-9
Toxicity-7
Treatment adherence-6
Inflammatory activity-5
Nutritional resilience+4

What helped?

No interventions yet.

LIFE OS recommendation

No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

Energy level

Daily log

6.2/10

stable · +0.1 vs previous 14 d

Stress level

Daily log

2.9/10

improving · -0.3 vs previous 14 d

Pessimism score

Daily log

4.1/10

improving · -0.2 vs previous 14 d

Sleep quality

Wearable

56.8/100

improving · +2.1 vs previous 14 d

Libido

Daily log

5.8/10

stable · +0.1 vs previous 14 d

HRV

Wearable

53.9 ms

stable · +1.8 vs previous 14 d

Toxicity

Blood

13.7/100

improving · -2.6 vs previous 14 d

This trajectory is doing well — what to keep, what to watch

Steering view →

Heading towards restoration · 74 from the failing basin, 42 from restoration.

Good elements to keep

Protein (supports)
perturbation · steering +11
Butyrate producers intact
hidden · steering +7.5
Protein
supporter · GI -5.6 next day

Main detractors to watch

Poor metabolizer
hidden · steering -12.7
Caffeine
perturbation · steering -7.7
Alcohol
perturbation · steering -7.5
Lactose
perturbation · steering -7.5
Caffeine
detractor · GI +4.4 next day
Alcohol
detractor · GI +4.4 next day

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Protein
-5.6supporter · 95%
Caffeine
+4.4detractor · 95%
Alcohol
+4.4detractor · 95%
Lactose
+4detractor · 95%
Dietary fat load
+1.8no signal · 49%
Histamine load
+0.2no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Drug metabolism and exposure ↑40
- DNACYP2D6 poor metabolizer → higher exposure

DNA

Fictional pharmacogenomic panel

CYP2D6 Poor metabolizer
Higher exposure at standard dose
MTHFR C677T
Reduced folate turnover

Microbiome

Shannon diversity 4.2 · butyrate capacity 57/100

Akkermansia muciniphilaNormal
Faecalibacterium prausnitziiNormal
Bacteroides fragilisNormal
Bifidobacterium longumNormal
EnterobacteriaceaeHigh

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 49 ms
Sleep: 6.6 h
Steps: 5,292
Resting HR: 71 bpm

Daily log: GI score 12, nutritional resilience 71, adherence 84.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Keep fibre steady; no new sources this week
Avoid known triggers for now: fried or oily food, dairy, alcohol

What to do

Log the daily check-in; one line is enough
Keep the current walking rhythm
Keep the sleep window steady
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the scheduled dose as agreed with your care team
No additional supplements this week
Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-03104	45%	S14	AD-05	no change	27
P-03034	37%	S14	AD-05	no change	30
P-03158	36%	S17	AD-05	no change	37
P-03369	36%	S18	AD-05	no change	37
P-03424	36%	S12	AD-05	improved	41
P-03380	35%	S16	AD-05	improved	34
P-03111	34%	S07	AD-05	no change	48
P-03122	33%	S13	AD-05	no change	40
P-03129	32%	S18	AD-05	no change	32
P-03204	31%	S16	AD-05	improved	48
P-03105	28%	S12	AD-05	no change	60
P-03441	27%	S19	AD-05	improved	37