Patient P-03426

Synthetic patientONX-7 · Day 135 · 25–34 · F · baseline S18Steering view · 3D Open companion preview

Therapy response

Unstable

Tolerance

Deteriorating

GI state

Improving

Inflammatory state

Improving

Nutritional resilience

Improving

Discontinuation risk

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 ONX-7 started — Baseline state S18
Day 32 Trajectory diverged from prediction — Observed response fell below the model's expected path.
Day 96 BR-03 recommended — Behavioural Recommendation BR-03
Day 97 Patient accepted — Started BR-03 in the companion
Day 104 GI symptom burden −13% vs expected — Behavioural Recommendation BR-03
Day 110 Tolerance state changed — Unstable → Improving

What changed?

Trajectory began diverging from predicted response on Day 32.

Primary contributors, last 14 days

GI instability-40
Inflammatory activity-23
Nutritional resilience+16
Treatment adherence-7
Toxicity+7

What helped?

Behavioural Recommendation BR-03Day 96
Result: symptom burden −13%

LIFE OS recommendation

No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

Energy level

Daily log

6.3/10

improving · +0.5 vs previous 14 d

Stress level

Daily log

3.6/10

stable · -0.0 vs previous 14 d

Pessimism score

Daily log

4.4/10

stable · -0.2 vs previous 14 d

Sleep quality

Wearable

82.2/100

improving · +5.0 vs previous 14 d

Libido

Daily log

4.6/10

stable · -0.1 vs previous 14 d

HRV

Wearable

54.7 ms

stable · +1.7 vs previous 14 d

Toxicity

Blood

19.5/100

worsening · +0.6 vs previous 14 d

This trajectory is decaying — what would help, what would not

Steering view →

Heading towards restoration · 88 from the failing basin, 55 from restoration.

Would help

No untried action with strong evidence. Compose one from primitives.
More protein
GI -5.1 next day on high-intake days · n 28

Would not help

AD-05 Adherence Support
only 29% improved among 14 similar
Keep lactose low
GI +5.3 next day on high-intake days · n 22

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Lactose
+5.3detractor · 95%
Protein
-5.1supporter · 95%
Dietary fat load
-1.4no signal · 26%
Histamine load
-0.2no signal · 15%
Alcohol
-0.2no signal · 15%
Caffeine
+0.1no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Inflammatory signalling ↓20
- MicrobiomeBacteroides fragilis expansion

DNA

Fictional pharmacogenomic panel

CYP2D6 Rapid metabolizer
Expected exposure
MTHFR C677T
Reduced folate turnover

Microbiome

Shannon diversity 4.3 · butyrate capacity 74/100

Akkermansia muciniphilaNormal
Faecalibacterium prausnitziiNormal
Bacteroides fragilisHigh
Bifidobacterium longumLow
EnterobacteriaceaeHigh

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 53 ms
Sleep: 7.8 h
Steps: 9,505
Resting HR: 67 bpm

Daily log: GI score 0, nutritional resilience 71, adherence 88.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Keep fibre steady; no new sources this week
Avoid known triggers for now: fried or oily food, dairy, alcohol

What to do

Log the daily check-in; one line is enough
Keep the current walking rhythm
Keep the sleep window steady
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the scheduled dose as agreed with your care team
No additional supplements this week
Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-03104	46%	S14	AD-05	no change	27
P-03369	37%	S18	AD-05	no change	37
P-03034	36%	S14	AD-05	no change	30
P-03129	36%	S18	AD-05	no change	32
P-03380	36%	S16	AD-05	improved	34
P-03122	35%	S13	AD-05	no change	40
P-03111	32%	S07	AD-05	no change	48
P-03158	32%	S17	AD-05	no change	37
P-03424	31%	S12	AD-05	improved	41
P-03204	28%	S16	AD-05	improved	48
P-03441	28%	S19	AD-05	improved	37
P-03105	25%	S12	AD-05	no change	60