Patient P-03444
Therapy response
Improving
Tolerance
Stable
GI state
Improving
Inflammatory state
Unstable
Nutritional resilience
Unstable
Discontinuation risk
56%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 ONX-7 started — Baseline state S17
- Day 103 Trajectory diverged from prediction — Observed response fell below the model's expected path.
What changed?
Trajectory began diverging from predicted response on Day 103.
Primary contributors, last 14 days
- GI instability-7
- Treatment adherence-4
- Toxicity+4
- Inflammatory activity+3
What helped?
No interventions yet.
LIFE OS recommendation
GI Support Protocol GI-04
58%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 82% showed improvement
- median effect visible after 8 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
Energy level
Daily log2.7/10
stable · -0.0 vs previous 14 d
Stress level
Daily log7.1/10
stable · -0.1 vs previous 14 d
Pessimism score
Daily log5.5/10
stable · -0.0 vs previous 14 d
Sleep quality
Wearable25.6/100
improving · +3.0 vs previous 14 d
Libido
Daily log2.4/10
stable · -0.1 vs previous 14 d
HRV
Wearable31 ms
stable · +1.0 vs previous 14 d
Toxicity
Blood50/100
stable · +1.5 vs previous 14 d
This trajectory is doing well — what to keep, what to watch
Steering view →Heading towards restoration · 40 from the failing basin, 56 from restoration.
Good elements to keep
- Butyrate producers intacthidden · steering +7.5
- Protein (supports)perturbation · steering +5.5
- Proteinsupporter · GI -3.6 next day
Main detractors to watch
- Rapid metabolizerhidden · steering -8
- Enterobacteriaceae elevatedhidden · steering -7.4
- Lactoseperturbation · steering -6.2
- Antibiotic courseperturbation · steering -4.7
- Lactosedetractor · GI +3.1 next day
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Protein-3.6supporter · 95%
- Lactose+3.1detractor · 95%
- Histamine load-0.9no signal · 27%
- Alcohol+0.9no signal · 23%
- Caffeine+0.4no signal · 15%
- Dietary fat load+0.3no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Drug metabolism and exposure ↑55
- DNADPYD *2A → slower clearance
- BloodToxicity index 50
- Mucosal barrier integrity ↓50
- MicrobiomeAkkermansia low → thinner mucus layer
- Daily logGI symptom score 56 and rising
- Butyrate / short-chain fatty acid production ↓45
- MicrobiomeF. prausnitzii depleted
- Daily logFibre intake low in recent food logs
- Inflammatory signalling ↑40
- BloodInflammatory load index 60
- WearableHRV 31 ms, trending down
- Autonomic recovery ↓25
- WearableResting HR 86 bpm
DNA
Fictional pharmacogenomic panel
- DPYD *2A heterozygousSlower drug clearance
- CYP2D6 Rapid metabolizerExpected exposure
- MTHFR C677TReduced folate turnover
Microbiome
Shannon diversity 3 · butyrate capacity 47/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisNormal
- Bifidobacterium longumLow
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 30 ms
- Sleep
- 6.7 h
- Steps
- 6,624
- Resting HR
- 87 bpm
Daily log: GI score 56, nutritional resilience 39, adherence 61.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- Keep the current walking rhythm
- Keep the sleep window steady
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.