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Patient P-03491

Synthetic patientONX-7 · Day 149 · 65–74 · M · baseline S07Steering view · 3DOpen companion preview
Therapy response
Unstable
Tolerance
Favorable
GI state
Improving
Inflammatory state
Improving
Nutritional resilience
Favorable
Discontinuation risk
12%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 ONX-7 started — Baseline state S07
  2. Day 10 Trajectory diverged from prediction — Observed response fell below the model's expected path.
  3. Day 128 DT-01 recommended — Dosing / Timing Recommendation DT-01
  4. Day 129 Patient accepted — Started DT-01 in the companion
  5. Day 134 No meaningful change — Dosing / Timing Recommendation DT-01

What changed?

Trajectory began diverging from predicted response on Day 10.

Primary contributors, last 14 days
  • GI instability-15
  • Inflammatory activity-15
  • Nutritional resilience+4
  • Treatment adherence+2

What helped?

  • Dosing / Timing Recommendation DT-01Day 128
    Result: no meaningful change
LIFE OS recommendation
No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

Energy level
Daily log
6.1/10
improving · +0.9 vs previous 14 d
Stress level
Daily log
4.5/10
improving · -0.7 vs previous 14 d
Pessimism score
Daily log
5.2/10
improving · -0.5 vs previous 14 d
Sleep quality
Wearable
46.4/100
improving · +9.5 vs previous 14 d
Libido
Daily log
5.1/10
improving · +0.5 vs previous 14 d
HRV
Wearable
41.2 ms
improving · +5.2 vs previous 14 d
Toxicity
Blood
12/100
worsening · +1.1 vs previous 14 d
This trajectory is doing well — what to keep, what to watch
Steering view →

Heading towards restoration · 74 from the failing basin, 51 from restoration.

Good elements to keep
  • Dosing / Timing Recommendation DT-01
    intervention · steering +8.9
  • Butyrate producers intact
    hidden · steering +7.5
  • Protein (supports)
    perturbation · steering +5.6
  • Protein
    supporter · GI -3 next day
Main detractors to watch
  • Poor metabolizer
    hidden · steering -12.7
  • FUT2 non-secretor
    hidden · steering -10.6
  • Bacteroides fragilis elevated
    hidden · steering -7.4
  • Histamine load
    perturbation · steering -5.4
  • Histamine load
    detractor · GI +3.1 next day
  • Alcohol
    detractor · GI +2.5 next day
State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

  • Histamine load
    +3.1detractor · 95%
  • Protein
    -3supporter · 95%
  • Alcohol
    +2.5detractor · 88%
  • Caffeine
    +2.1detractor · 71%
  • Lactose
    +1.6no signal · 47%
  • Dietary fat load
    +0.6no signal · 19%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure
  • Drug metabolism and exposure ↑40
    • DNACYP2D6 poor metabolizer → higher exposure
  • Mucosal barrier integrity ↓30
    • DNAFUT2 non-secretor lowers mucosal fucosylation
  • Inflammatory signalling ↓20
    • MicrobiomeBacteroides fragilis expansion
  • Autonomic recovery ↑20
    • Wearable2,737 steps/day
DNA
Fictional pharmacogenomic panel
  • FUT2 rs601338 AA (non-secretor)
    Reduced mucosal fucosylation
  • CYP2D6 Poor metabolizer
    Higher exposure at standard dose
Microbiome
Shannon diversity 3 · butyrate capacity 51/100
  • Akkermansia muciniphilaNormal
  • Faecalibacterium prausnitziiNormal
  • Bacteroides fragilisHigh
  • Bifidobacterium longumNormal
  • EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
HRV
43 ms
Sleep
6.9 h
Steps
4,132
Resting HR
65 bpm
Daily log: GI score 16, nutritional resilience 65, adherence 86.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview
What to eat
  • Keep meals regular; three to four moderate portions spaced through the day
  • Include a cooked vegetable portion with each main meal
  • Keep fibre steady; no new sources this week
  • Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
  • Log the daily check-in; one line is enough
  • A 15-minute walk after lunch
  • Keep the sleep window steady
  • Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
  • Take the scheduled dose as agreed with your care team
  • No additional supplements this week
  • Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Sort by similaritySort by interventionSort by outcomeSort by stateSort by response
PatientSimilarityBaselineInterventionOutcomeResponse today
P-0301349%S07GI-04improved30
P-0323544%S13GI-04improved29
P-0342644%S18BR-03improved27
P-0337337%S17BR-03improved34
P-0338035%S16AD-05improved34
P-0327734%S14BR-03improved41
P-0330734%S03ME-01improved17
P-0323332%S19DT-01improved47
P-0342432%S12AD-05improved41
P-0321531%S16HY-01improved44
P-0320430%S16AD-05improved48
P-0344229%S11DT-01improved51