DeepGene damage signature
SyntheticSynthetic demo data2 samples: baseline day 0 · retest day 90
Damage score · retest day 90
36/100
vs baseline (day 0)
+11
0 improved · 5 worsened
synthetic signature · consistent with this patient's biology
- 3 opportunists above range: Klebsiella pneumoniae, Enterococcus faecium, Clostridioides difficile
- 2 keystone species absent
- 4 resistance genes
Pathogens / opportunists3/5
↑ from 1
Keystone species2/8
Diversity0/2
Metabolic modules1/4
↑ from 0
Vitamin synthesis2/7
↑ from 1
Oral translocation1/1
Host DNA0/1
Tissue recycling0/1
Central mechanisms0/2
Virulence factors2/2
Antibiotic resistance genes4/4
↑ from 3
Genetic predisposition2/2
Opportunists above range
Enterococcus faecium 5.484% AR
Klebsiella pneumoniae 3.291% AR
Clostridioides difficile 1.097% AR
Keystone species absent
Akkermansia muciniphila, Bifidobacterium longum
Capacity
Shannon 3.2 · butyrate 768 CPM · SCFA 1159
H2S above band
2 vitamins below
Host & mechanisms
tissue recycling 29/100
oral translocation 2.52% AR
4 resistance genes · 2 virulence factors
Import a sample
A baseline sample re-initializes this patient's microbiome, pathways and predispositions from the measurement; a retest adds a comparison and updates them. Every theory, steering gain and dietary sensitivity downstream is then conditioned on the measured signature.
All elements · baseline → latest
Value, status vs the expected range, and the implication on health. Changes coloured: green improved / resolved, red worsened / new.
Pathogens / opportunists · 5
| Escherichia coli | 0.795 % AR · in range | 0.768 % AR · in range | expected <= 1% | In excess raises LPS load and zonulin release, opening tight junctions. |
| Klebsiella pneumoniae | 3.011 % AR · above range | 3.291 % AR · above range | expected <= 0.3% | Opportunist above range; relevant after antibiotics and in inflammation. |
| Enterococcus faecium | 0.151 % AR · in range | 5.484 % AR · above range(worsened) | expected <= 0.5% | Opportunist above range; relevant after antibiotics and in inflammation. |
| Streptococcus gallolyticus | 0.079 % AR · in range | 0.003 % AR · in range | expected <= 0.1% | Opportunist above range; relevant after antibiotics and in inflammation. |
| Clostridioides difficile | 0.056 % AR · in range | 1.097 % AR · above range(worsened) | expected <= 0.1% | Opportunist above range; relevant after antibiotics and in inflammation. |
Keystone species · 8
| Akkermansia muciniphila | 0 % AR · absent | 0 % AR · absent | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Bifidobacterium longum | 0 % AR · absent | 0 % AR · absent | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Butyricicoccus pullicaecorum | 1.43 % AR · in range | 1.46 % AR · in range | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Eubacterium rectale | 0.04 % AR · in range | 1.02 % AR · in range | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Faecalibacterium prausnitzii | 1 % AR · in range | 0.03 % AR · in range | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Lactobacillus species | 1.31 % AR · in range | 1.2 % AR · in range | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Roseburia intestinalis | 1.26 % AR · in range | 0.52 % AR · in range | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Ruminococcus bromii | 0 % AR · in range | 1.2 % AR · in range | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
Diversity · 2
| indice Shannon | 3.12 · in range | 3.2 · in range | expected >= 3.0 | Low diversity: fewer reserve metabolic routes, slower recovery after perturbation. |
| numar de specii detectate | 134 specii · in range | 140 specii · in range | expected >= 100 | Species count below reference. |
Metabolic modules · 4
| Butyrate production | 749 CPM · in range | 768 CPM · in range | expected 255.83-1089.91 CPM | Butyrate is the main colonocyte fuel and barrier signal. |
| Short Chain Fatty Acid Production | 1229 CPM · in range | 1159 CPM · in range | expected 535.03-1572.59 CPM | Total SCFA capacity. |
| GABA production | 420 CPM · in range | 398 CPM · in range | expected 87.31-766.53 CPM | Gut–brain axis capacity. |
| H2S production (sulfate reduction) | 124 CPM · in range | 364 CPM · above range(worsened) | expected banda de referinta | Hydrogen sulfide above band irritates the mucosa. |
Vitamin synthesis · 7
| Vitamin B1 - Thiamin | 481 CPM · below range | 505 CPM · below range | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B2 - Riboflavin | 4141 CPM · in range | 260 CPM · below range(worsened) | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B5 - Pantothenic acid | 4061 CPM · in range | 4421 CPM · in range | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B6 - Pyridoxine | 2851 CPM · in range | 3621 CPM · in range | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B7 - Biotin | 3844 CPM · in range | 2595 CPM · in range | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B9 - Folate | 4029 CPM · in range | 4225 CPM · in range | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B12 - Cobalamin | 3397 CPM · in range | 4034 CPM · in range | expected 2000-5000 CPM | Microbial synthesis capacity. |
Oral translocation · 1
| Translocare orala (indice) | 2.31 % AR · above range | 2.52 % AR · above range | expected <= 2% | Oral taxa in stool: reduced gastric barrier or dysbiosis. |
Host DNA · 1
| fragmentare mixta | 160 pb · in range | 159 pb · in range | expected 150-170 pb | Host cell-free DNA fragmentation pattern. |
Tissue recycling · 1
| indice de reciclare tisulara | 28 /100 · in range | 29 /100 · in range | expected < 35 | Epithelial turnover. |
Central mechanisms · 2
| molecular_mimicry | 55 /100 · in range | 57 /100 · in range | expected < 65 | Cross-reactive antigen load. |
| estrobolome | 55 /100 · in range | 53 /100 · in range | expected < 65 | Estrogen-recycling capacity. |
Virulence factors · 2
| fimD outer membrane usher | 67 potriviri/M · present | 30 potriviri/M · present | expected absent | Virulence factor detected. |
| chuA heme/hemoglobin receptor | 54 potriviri/M · present | 30 potriviri/M · present | expected absent | Virulence factor detected. |
Antibiotic resistance genes · 4
| sul1 | 5 citiri/M · present | 2.8 citiri/M · present | expected nedetectat | Resistance gene detected. |
| sul2 | 4.7 citiri/M · present | 1.6 citiri/M · present | expected nedetectat | Resistance gene detected. |
| tet(O/M/O) | 6.1 citiri/M · present | 3.3 citiri/M · present | expected nedetectat | Resistance gene detected. |
| Ecol_ampC_BLA | — | 7.4 citiri/M · present(new) | expected nedetectat | Resistance gene detected. |
Genetic predisposition · 2
| CYP2D6 | 3.14 OR · risk variant | 2.28 OR · risk variant | expected reference genotype | Expected exposure |
| GLP1R | 2.09 OR · risk variant | 2.56 OR · risk variant | expected reference genotype | Altered receptor sensitivity |