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Patient P-02019

Synthetic patientMETA-24 · Day 169 · 65–74 · M · baseline S12Steering view · 3DOpen companion preview
Therapy response
Stable
Tolerance
Improving
GI state
Favorable
Inflammatory state
Favorable
Nutritional resilience
Stable
Discontinuation risk
27%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 META-24 started — Baseline state S12
  2. Day 86 Trajectory diverged from prediction — Observed response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 86.

Primary contributors, last 14 days
  • Toxicity-5
  • GI instability+3
  • Nutritional resilience-2

What helped?

No interventions yet.

    LIFE OS recommendation
    No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

    Daily trackers

    Molecule settings

    The trackers this program marks as important, last 14 days vs the 14 before.

    Active minutes
    Wearable
    52 min
    stable · +0.5 vs previous 14 d
    Sleep duration
    Wearable
    5.4 h
    stable · -0.2 vs previous 14 d
    Energy level
    Daily log
    5.2/10
    stable · +0.1 vs previous 14 d
    Steps
    Wearable
    5,663
    stable · +105 vs previous 14 d
    GI burden
    Companion
    34.6/100
    worsening · +3.1 vs previous 14 d
    Adherence
    Companion
    91.5 %
    stable · -0.6 vs previous 14 d
    Sleep quality
    Wearable
    30.2/100
    worsening · -3.2 vs previous 14 d
    Glucose, CGM daily mean
    CGM
    134 mg/dL
    stable · -0.6 vs previous 14 d
    This trajectory is doing well — what to keep, what to watch
    Steering view →

    Heading towards restoration · 55 from the failing basin, 33 from restoration.

    Good elements to keep
    • Protein (supports)
      perturbation · steering +13.5
    • Butyrate producers intact
      hidden · steering +7.5
    • Daily walks resumed
      perturbation · steering +3.3
    • Protein
      supporter · GI -7.5 next day
    Main detractors to watch
    • FUT2 non-secretor
      hidden · steering -10.6
    • Ultra-processed food
      perturbation · steering -10.2
    • Histamine load
      perturbation · steering -10.1
    • Bacteroides fragilis elevated
      hidden · steering -7.4
    • Histamine load
      detractor · GI +6.3 next day
    • Ultra-processed food
      detractor · GI +6.1 next day
    State influencers · digestive

    Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

    • Protein
      -7.5supporter · 95%
    • Histamine load
      +6.3detractor · 95%
    • Ultra-processed food
      +6.1detractor · 95%
    • Dietary fat load
      +2no signal · 36%
    • Caffeine
      +1.9no signal · 36%
    • Insoluble fibre
      +1.4no signal · 22%
    • Simple carbohydrates
      -0.6no signal · 15%
    • Alcohol
      -0.2no signal · 15%

    Biological layers

    Which pathways look influenced, and by which layer of this person's biology.

    Pathways under pressure
    • Mucosal barrier integrity ↓70
      • DNAFUT2 non-secretor lowers mucosal fucosylation
      • MicrobiomeAkkermansia low → thinner mucus layer
      • WearableSleep 5.4 h, below personal baseline
    • Inflammatory signalling ↓45
      • DNAIL6 -174 variant raises baseline inflammatory tone
      • MicrobiomeBacteroides fragilis expansion
    • Autonomic recovery ↑20
      • WearableShort sleep window
    DNA
    Fictional pharmacogenomic panel
    • FUT2 rs601338 AA (non-secretor)
      Reduced mucosal fucosylation
    • IL6 -174 G/C
      Higher inflammatory tone
    • CYP2D6 Normal metabolizer
      Expected exposure
    • GLP1R rs6923761 A
      Altered receptor sensitivity
    Microbiome
    Shannon diversity 3.6 · butyrate capacity 80/100
    • Akkermansia muciniphilaLow
    • Faecalibacterium prausnitziiNormal
    • Bacteroides fragilisHigh
    • Bifidobacterium longumLow
    • EnterobacteriaceaeHigh
    Wearable, last 14 days
    daily evolution fed into the runtime
    HRV
    43 ms
    Sleep
    6.1 h
    Steps
    5,297
    Resting HR
    60 bpm
    Daily log: GI score 35, nutritional resilience 54, adherence 92.

    What this patient sees in NostraAI

    The content that steers the trajectory: what to eat, what to do, what to take.

    Open companion preview
    What to eat
    • Keep meals regular; three to four moderate portions spaced through the day
    • Include a cooked vegetable portion with each main meal
    • Keep fibre steady; no new sources this week
    • Eat slowly and stop at comfortable fullness — smaller volume, more often
    What to do
    • Log the daily check-in; one line is enough
    • Keep the current walking rhythm
    • Protect a 7.5-hour sleep window; screens off 30 minutes before
    • Keep hydration steady: small amounts through the day rather than large volumes at once
    What to take
    • Take the dose at the same time relative to your evening meal
    • No additional supplements this week
    • Fictional demo item: continue vitamin D as before

    284 biologically similar trajectories

    Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

    Sort by similaritySort by interventionSort by outcomeSort by stateSort by response
    PatientSimilarityBaselineInterventionOutcomeResponse today
    P-0246242%S12DT-01improved65
    P-0227440%S15DT-01improved50
    P-0259939%S14HY-01improved54
    P-0223538%S14DT-01improved50
    P-0248437%S15GI-04improved49
    P-0251837%S17DT-01improved68
    P-0253837%S02GI-04improved59
    P-0264537%S02HY-01improved56
    P-0203336%S06GI-04improved51
    P-0208236%S12NP-02improved53
    P-0215036%S11HY-01improved45
    P-0245936%S05HY-01improved52